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In vivo radiobiological assessment of the new clinical varbon ion beams at CNAO
https://repo.qst.go.jp/records/47372
https://repo.qst.go.jp/records/47372b464c164-6b25-4f79-8f95-e4f7eebf51b4
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2016-01-18 | |||||
| タイトル | ||||||
| タイトル | In vivo radiobiological assessment of the new clinical varbon ion beams at CNAO | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
FACOETTI, Angelica
× FACOETTI, Angelica× Barbara, Vischioni× Ciocca, M.× Ferrarini, M.× 古澤, 佳也× Mairani, A.× 松本, 孔貴× Mirandola, A.× Molinelli, S.× 鵜澤, 玲子× G., Vilches Freixas× R.Orecchia× Ｖｉｓｃｈｉｏｎｉ Ｂａｒｂａｒａ× 古澤 佳也× 松本 孔貴× 鵜澤 玲子 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | In this article, the in vivo study performed to evaluate the uniformity of biological doses within an hypothetical target volume and calculate the values of relative biological effectiveness (RBE) at different depths in the spread-out Bragg peak (SOBP) of the new CNAO (National Centre for Oncological Hadrontherapy) carbon beams is presented, in the framework of a typical radiobiological beam calibration procedure. The RBE values (relative to 60Co g rays) of the CNAO active scanning carbon ion beams were determined using jejunal crypt regeneration in mice as biological system at the entrance, centre and distal end of a 6-cm SOBP. The RBE values calculated from the iso-effective doses to reduce crypt survival per circumference to 10, ranged from 1.52 at the middle of the SOBP to 1.75 at the distal position and are in agreement with those previously reported from other carbon ion facilities. In conclusion, this first set of in vivo experiments shows that the CNAO carbon beam is radiobiologically comparable with the NIRS (National Institute of Radiological Sciences, Chiba, Japan) and GSI (Helmholtzzentrum fu¨r Schwerionenforschung, Darmstadt, Germany) ones. | |||||
| 書誌情報 |
Radiation Protection Dosimetry 巻 166, 号 1-4, p. 379-382, 発行日 2015-09 |
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| 出版者 | ||||||
| 出版者 | Oxford University Press | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0144-8420 | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 25877541 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1093/rpd/ncv145 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://rpd.oxfordjournals.org/content/early/2015/04/15/rpd.ncv145 | |||||
| 関連名称 | http://rpd.oxfordjournals.org/content/early/2015/04/15/rpd.ncv145 | |||||
