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Wavelet denoising for voxel-based compartmental analysis of peripheral benzodiazepine receptors with 18F-FEDAA1106
https://repo.qst.go.jp/records/47333
https://repo.qst.go.jp/records/473338b03c15e-0a9a-4fce-aa57-75c69e78fb75
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2015-11-13 | |||||
| タイトル | ||||||
| タイトル | Wavelet denoising for voxel-based compartmental analysis of peripheral benzodiazepine receptors with 18F-FEDAA1106 | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Shidahara, Miho
× Shidahara, Miho× Ikoma, Yoko× Seki, Chie× Fujimura, Yota× Naganawa, Mika× Ito, Hiroshi× Suhara, Tetsuya× Kanno, Iwao× Kimura, Yuichi× 志田原 美保× 生駒 洋子× 関 千江× 藤村 洋太× 長縄 美香× 伊藤 浩× 須原 哲也× 菅野 巖× 木村 裕一 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Purpose: We evaluated the noise reduction capability of wavelet denoising for estimated binding potential (BP) images (k 3/k 4) of the peripheral benzodiazepine receptor using 18F-FEDAA1106 and nonlinear least-square fitting. Methods: Wavelet denoising within a three-dimensional discrete dual-tree complex wavelet transform was applied to simulate data and clinical dynamic positron emission tomography images of 18F-FEDAA1106. To eliminate noise components in wavelet coefficients, real and imaginary coefficients for each subband were thresholded individually using NormalShrink. A simulated dynamic brain image of 18F-FEDAA1106 was generated and Gaussian noise was added to mimic PET dynamic scan. The derived BP images were compared with true images using 156 rectangular regions of interest. Wavelet denoising was also applied to data derived from seven young normal volunteers. Results: In the simulations, estimated BP by denoised image showed better correlation with the true BP values (Y=0.83X+0.94, r=0.80), although no correlation was observed in the estimates between noise-added and true images (Y=1.2X+0.78, r=0.49). For clinical data, there were visual improvements in the signal-to-noise ratio for estimated BP images. Conclusions: Wavelet denoising improved the bias and reduced the variation of pharmacokinetic parameters for BP. |
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| 書誌情報 |
European Journal of Nuclear Medicine and Molecular Imaging 巻 35, 号 2, p. 416-423, 発行日 2007-11 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1619-7070 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1007/s00259-007-0623-y | |||||
