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  1. 原著論文

Local effect of stereotactic body radiotherapy for primary and metastatic liver tumors in 130 Japanese patients.

https://repo.qst.go.jp/records/47236
https://repo.qst.go.jp/records/47236
d864470c-3351-4bfd-bd16-8cfbcc26a1eb
Item type 学術雑誌論文 / Journal Article(1)
公開日 2015-08-07
タイトル
タイトル Local effect of stereotactic body radiotherapy for primary and metastatic liver tumors in 130 Japanese patients.
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Yamashita, Hideomi

× Yamashita, Hideomi

WEKO 472362

Yamashita, Hideomi

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Onishi, Hiroshi

× Onishi, Hiroshi

WEKO 472363

Onishi, Hiroshi

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Matsumoto, Yasuo

× Matsumoto, Yasuo

WEKO 472364

Matsumoto, Yasuo

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Murakami, Naoya

× Murakami, Naoya

WEKO 472365

Murakami, Naoya

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Matsuo, Yukinori

× Matsuo, Yukinori

WEKO 472366

Matsuo, Yukinori

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Nomiya, Takuma

× Nomiya, Takuma

WEKO 472367

Nomiya, Takuma

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Nakagawa, Keiichi

× Nakagawa, Keiichi

WEKO 472368

Nakagawa, Keiichi

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野宮 琢磨

× 野宮 琢磨

WEKO 472369

en 野宮 琢磨

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抄録
内容記述タイプ Abstract
内容記述 BACKGROUND AND AIMS: Stereotactic body radiotherapy (SBRT) is a relatively new treatment for liver tumor. The outcomes of SBRT for liver tumor unfit for ablation and surgical resection were evaluated.
METHODS: Liver tumor patients treated with SBRT in seven Japanese institutions were studied retrospectively. Patients given SBRT for liver tumor between 2004 and 2012 were collected. Patients treated with SBRT preceded by trans-arterial chemoembolization (TACE) were eligible. Seventy-nine patients with hepatocellular carcinoma (HCC) and 51 patients with metastatic liver tumor were collected. The median biologically effective dose (BED) (α/β = 10 Gy) was 96.3 Gy for patients with HCC and 105.6 Gy with metastatic liver tumor.
RESULTS: The median follow-up time was 475.5 days in patients with HCC and 212.5 days with metastatic liver tumor. The 2-year local control rate (LCR) for HCC and metastatic liver tumor was 74.8% ± 6.3% and 64.2 ± 9.5% (p = 0.44). The LCR was not different between BED10 ≥ 100 Gy and < 100 Gy (p = 0.61). The LCR was significantly different between maximum tumor diameter > 30 mm vs. ≤ 30 mm (64% vs. 85%, p = 0.040) in all 130 patients. No grade 3 laboratory toxicities in the acute, sub-acute and chronic phases were observed.
CONCLUSIONS: There was no difference in local control after SBRT in the range of median BED10 around 100 Gy for between HCC and metastatic liver tumor. SBRT is safe and might be an alternative method to resection and ablation.
SUMMARY: There was no difference in local control after SBRT in the range of median BED10 around 100 Gy for between HCC and metastatic liver tumor and SBRT is safe and might be an alternative method to resection and ablation.
書誌情報 Radiation oncology (London, England)

巻 9, p. 112, 発行日 2014-01
出版者
出版者 BioMed Central
ISSN
収録物識別子タイプ ISSN
収録物識別子 1748-717X
PubMed番号
識別子タイプ PMID
関連識別子 24886477
DOI
識別子タイプ DOI
関連識別子 10.1186/1748-717X-9-112
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