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Reproducibility of PET measurement for presynaptic dopaminergic functions using L-[β-(11)C]DOPA and [(18)F]FE-PE2I in humans.
https://repo.qst.go.jp/records/47215
https://repo.qst.go.jp/records/47215e091f86a-3883-48d5-9247-21d4933c7537
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2015-08-06 | |||||
| タイトル | ||||||
| タイトル | Reproducibility of PET measurement for presynaptic dopaminergic functions using L-[β-(11)C]DOPA and [(18)F]FE-PE2I in humans. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Suzuki, Masayuki
× Suzuki, Masayuki× Ito, Hiroshi× Kodaka, Fumitoshi× Takano, Harumasa× Kimura, Yasuyuki× Fujiwara, Hironobu× Sasaki, Takeshi× Takahata, Keisuke× Nogami, Tsuyoshi× Nagashima, Tomohisa× Nengaki, Nobuki× Kawamura, Kazunori× Zhang, Ming-Rong× Varrone, Andrea× Halldin, Christer× Okubo, Yoshiro× Suhara, Tetsuya× 鈴木 雅之× 伊藤 浩× 小高 文聰× 高野 晴成× 木村 泰之× 藤原 広臨× 佐々木 健至× 高畑 圭輔× 野上 毅× 永嶌 朋久× 念垣 信樹× 河村 和紀× 張 明栄× 大久保 善朗× 須原 哲也 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Recent PET studies have indicated altered presynaptic function and relation with psychotic symptoms in patients with schizophrenia. The L-[β-(11)C]DOPA uptake rate reflects the dopamine synthesis capacity (kref), whereas the nondisplaceable binding potential (BPND) of [(18)F]FE-PE2I reflects the dopamine transporter availability. Although the kref values of L-[β-(11)C]DOPA and the BPND of [(18)F]FE-PE2I can be potential markers for evaluating the severity of positive symptoms, test-retest reproducibility has not been confirmed. The purpose of this study was to investigate the test-retest reproducibility of kref values of L-[β-(11)C]DOPA and that of BPND of [(18)F]FE-PE2I in the striatum and midbrain in healthy humans. | |||||
| 書誌情報 |
Nuclear medicine communications 巻 35, 号 3, p. 231-237, 発行日 2014-03 |
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| 出版者 | ||||||
| 出版者 | Lippincott Williams & Wilkins | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0143-3636 | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 24468851 | |||||
