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Implementation of a target volume design function for intrafractional range variation in a particle beam treatment planning system
https://repo.qst.go.jp/records/47182
https://repo.qst.go.jp/records/47182a36c92f0-bf4e-412d-aa09-68ef0e852a26
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2015-07-23 | |||||
| タイトル | ||||||
| タイトル | Implementation of a target volume design function for intrafractional range variation in a particle beam treatment planning system | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Mori, Shinichiro
× Mori, Shinichiro× Inaniwa, Taku× Miki, Kentaro× Shirai, Toshiyuki× Noda, Koji× 森 慎一郎× 稲庭 拓× 三木 健太朗× 白井 敏之× 野田 耕司 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Objective: Treatment planning for charged particle therapy in the thoracic and abdominal regions should take account of range uncertainty due to intrafractional motion. Here, we developed a design tool (4Dtool) for the target volume [field-specific target volume (FTV)], which accounts for this uncertainty using four-dimensional CT (4DCT). Methods: Target and normal tissue contours were input manually into a treatment planning system (TPS). These data were transferred to the 4Dtool via the picture archiving and communication system (PACS). Contours at the reference phase were propagated to other phases by deformable image registration. FTV was calculated using 4DCT on the 4Dtool. The TPS displays FTV contours using digital imaging and communications in medicine files imported from the PACS. These treatment parameters on the CT image at the reference phase were then used for dose calculation on the TPS. The tool was tested in single clinical case randomly selected from patients treated at our centre for lung cancer. Results: In this clinical case, calculation of dose distribu- tion with the 4Dtool resulted in the successful delivery of carbon-ion beam at the reference phase of 95% of the prescribed dose to the clinical target volume (CTV). Application to the other phases also provided sufficient dose to the CTV. Conclusion: The 4Dtool software allows the design of the target volume with consideration to intrafractional range variation and is now in routine clinical use at our institution. Advances in knowledge: Our alternative technique represents a practical approach to four-dimensional treatment planning within the current state of charged particle therapy. |
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| 書誌情報 |
The British Journal of Radiology 巻 87, 号 1043, p. 20140233-1-20140233-8, 発行日 2015-02 |
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| 出版者 | ||||||
| 出版者 | The British Institute of Radiology | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0007-1285 | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 25168286 | |||||
