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Imaging of amyloid deposition in human brain using positron emission tomography and [(18)F]FACT: comparison with [ (11)C]PIB.
https://repo.qst.go.jp/records/47097
https://repo.qst.go.jp/records/47097fa97bd1f-a32e-4a46-82d0-6aad6363a7f7
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2015-04-20 | |||||
| タイトル | ||||||
| タイトル | Imaging of amyloid deposition in human brain using positron emission tomography and [(18)F]FACT: comparison with [ (11)C]PIB. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Ito, Hiroshi
× Ito, Hiroshi× Shinotoh, Hitoshi× Shimada, Hitoshi× Miyoshi, Michie× Yanai, Kazuhiko× Okamura, Nobuyuki× Takano, Harumasa× Takahashi, Hidehiko× Arakawa, Ryosuke× Kodaka, Fumitoshi× Ono, Maiko× Eguchi, Yoko× Higuchi, Makoto× Fukumura, Toshimitsu× Suhara, Tetsuya× 伊藤 浩× 島田 斉× 三好 美智恵× 岡村 信行× 高野 晴成× 高橋 英彦× 荒川 亮介× 小高 文聰× 小野 麻衣子× 江口 洋子× 樋口 真人× 福村 利光× 須原 哲也 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The characteristic neuropathological changes in Alzheimer's disease (AD) are deposition of amyloid senile plaques and neurofibrillary tangles. The (18)F-labeled amyloid tracer, [(18)F]2-[(2-{(E)-2-[2-(dimethylamino)-1,3-thiazol-5-yl]vinyl}-1,3-benzoxazol-6-yl)oxy]-3-fluoropropan-1-ol (FACT), one of the benzoxazole derivatives, was recently developed. In the present study, deposition of amyloid senile plaques was measured by positron emission tomography (PET) with both [(11)C]Pittsburgh compound B (PIB) and [(18)F]FACT in the same subjects, and the regional uptakes of both radiotracers were directly compared. | |||||
| 書誌情報 |
European journal of nuclear medicine and molecular imaging 巻 41, 号 4, p. 745-754, 発行日 2013-11 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1619-7070 | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 24233004 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1007/s00259-013-2620-7 | |||||
