WEKO3
アイテム
Health-related quality of life after carbon-ion radiotherapy for prostate cancer: A 3-year prospective study.
https://repo.qst.go.jp/records/46970
https://repo.qst.go.jp/records/469700c1172ab-c5ec-45f2-9adc-f10d87b2657d
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2014-11-27 | |||||
| タイトル | ||||||
| タイトル | Health-related quality of life after carbon-ion radiotherapy for prostate cancer: A 3-year prospective study. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Katoh, Hiroyuki
× Katoh, Hiroyuki× Tsuji, Hiroshi× Ishikawa, Hitoshi× Kamada, Tadashi× Wakatuki, Masaru× Hirasawa, Naoki× Suzuki, Hiroyoshi× Akakura, Koichiro× Nakano, Takashi× Shimazaki, Jun× Tsujii, Hirohiko× 辻 比呂志× 鎌田 正× 若月 優× 辻井 博彦 |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | OBJECTIVES: \nTo assess 3-year health-related quality of life of patients treated with carbon ion radiotherapy for prostate cancer. \nMETHODS: \nA total of 213 patients received carbon-ion radiotherapy at a total dose of 66 Gy equivalent in 20 fractions over 5 weeks, and neoadjuvant and adjuvant androgen deprivation therapy were administered for high-risk patients for at least 12 months. A health-related quality of life assessment was carried out at four time-points (immediately before the initiation of carbon-ion radiotherapy, immediately after, 12 and 36 months after completion of carbon-ion radiotherapy) using Functional Assessment of Cancer Therapy General and for Prostate Cancer Patients. \nRESULTS: \nThe evaluable response rates among all responses were more than 94%. Overall, a significant decrease in the scores of the health-related quality of life 12 months after carbon-ion radiotherapy returned to their baseline levels at 36 months. Additionally, no significant decrease was observed in the scores at any of the assessment time-points compared with their baseline scores in the group of carbon-ion radiotherapy without androgen deprivation therapy; however, the presence of morbidity and biochemical failure significantly worsened the scores, and the decreases in the scores did not improve even at 36 months after carbon-ion radiotherapy. \nCONCLUSIONS: \nAn assessment based on a subjective scoring system shows a significant decrease in health-related quality of life at 12 months after carbon-ion radiation therapy, which tends to return to baseline levels at 36 months. The presence of morbidity and biochemical failure significantly worsen health-related quality of life scores. Further controlled studies focusing on health-related quality of life assessment in patients with prostate cancer are warranted. |
|||||
| 書誌情報 |
International journal of urology : official journal of the Japanese Urological Association 巻 21, 号 4, p. 370-375, 発行日 2014-01 |
|||||
| 出版者 | ||||||
| 出版者 | Blackwell Science Asia | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0919-8172 | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 24118233 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1111/iju.12294 | |||||
