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A Microdosimetric-Kinetic Model for Cell Killing by Protracted Continuous Irradiation II: Brachytherapy and Biologic Effective Dose
https://repo.qst.go.jp/records/46803
https://repo.qst.go.jp/records/46803c1aff0bd-f863-4370-8a4d-ab83e0c3b1d8
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2014-08-08 | |||||
| タイトル | ||||||
| タイトル | A Microdosimetric-Kinetic Model for Cell Killing by Protracted Continuous Irradiation II: Brachytherapy and Biologic Effective Dose | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
B., Hawkins Roland
× B., Hawkins Roland× Inaniwa, Taku× 稲庭 拓 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Relationships based on the microdosimetric-kinetic model are presented that calculate the average number of lethal lesions, and the associated cell survival, produced in mammalian cells by exposure to protracted continuous irradiation by temporary and permanent implantation of radioactive sources. The influence of cell parameters of linear-quadratic survival, repair function and proliferation rate, as well as the influence of dose rate, isotopic decay rate and linear energy transfer (LET) quality on cell killing are displayed and discussed. An expression for biologic effective dose (BED) is presented that facilitates comparison of the effects of protracted low-dose-rate irradiation and with a course of multiple instantaneously administered radiation treatments (fractions). | |||||
| 書誌情報 |
Radiation Research 巻 182, 号 1, p. 72-82, 発行日 2014-07 |
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| 出版者 | ||||||
| 出版者 | Radiation Research Society | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0033-7587 | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 24937780 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | doi: http://dx.doi.org/10.1667/RR13558.1 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.bioone.org/doi/abs/10.1667/RR13558.1 | |||||
| 関連名称 | http://www.bioone.org/doi/abs/10.1667/RR13558.1 | |||||
