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Clinical outcome of sacral Chordoma with Carbon Ion Radiotherapy Compared with Surgery
https://repo.qst.go.jp/records/46767
https://repo.qst.go.jp/records/46767c0a8ca99-f7de-43ef-8f9a-a136626a0041
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2014-06-27 | |||||
| タイトル | ||||||
| タイトル | Clinical outcome of sacral Chordoma with Carbon Ion Radiotherapy Compared with Surgery | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Nishida, Yoshihiro
× Nishida, Yoshihiro× Kamada, Tadashi× Imai, Reiko× Tsukushi, Satoshi× Yamada, Yoshihisa× Sugiura, Hideshi× Shido, Yoji× Wasa, Junji× Ishiguro, Naoki× 鎌田 正× 今井 礼子 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | PURPOSE: To evaluate the efficacy, post-treatment function, toxicity, and complications of carbon ion radiotherapy (RT) for sacral chordoma compared with surgery. METHODS AND MATERIALS: The records of 17 primary sacral chordoma patients treated since 1990 with surgery (n=10) or carbon ion RT (n=7) were retrospectively analyzed for disease-specific survival, local recurrence-free survival, complications, and functional outcome. The applied carbon ion dose ranged from 54.0 Gray equivalent (GyE) to 73.6 GyE (median 70.4). RESULTS: The mean age at treatment was 55 years for the surgery group and 65 years for the carbon ion RT group. The median duration of follow-up was 76 months for the surgery group and 49 months for the carbon ion RT group. The local recurrence-free survival rate at 5 years was 62.5% for the surgery and 100% for the carbon ion RT group, and the disease-specific survival rate at 5 years was 85.7% and 53.3%, respectively. Urinary-anorectal function worsened in 6 patients (60%) in the surgery group, but it was unchanged in all the patients who had undergone carbon ion RT. Postoperative wound complications requiring reoperation occurred in 3 patients (30%) after surgery and in 1 patient (14%) after carbon ion RT. The functional outcome evaluated using the Musculoskeletal Tumor Society scoring system revealed 55% in the surgery group and 75% in the carbon ion RT group. Of the six factors in this scoring system, the carbon ion RT group had significantly greater scores in emotional acceptance than did the surgery group. CONCLUSION: Carbon ion RT results in a high local control rate and preservation of urinary-anorectal function compared with surgery. | |||||
| 書誌情報 |
International Journal of Radiation Oncology Biology Physics 巻 79, 号 1, p. 110-116, 発行日 2011-01 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0360-3016 | |||||
