ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

  1. 原著論文

Compatibility of the repairable-conditionally repairable, multi-target and linear-quadratic models in converting hypofractionated radiation doses to single doses

https://repo.qst.go.jp/records/46632
https://repo.qst.go.jp/records/46632
83a8a465-a632-47a4-9bd5-b6d2644b6af2
Item type 学術雑誌論文 / Journal Article(1)
公開日 2013-11-26
タイトル
タイトル Compatibility of the repairable-conditionally repairable, multi-target and linear-quadratic models in converting hypofractionated radiation doses to single doses
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Iwata, Hiromitsu

× Iwata, Hiromitsu

WEKO 464901

Iwata, Hiromitsu

Search repository
Matsufuji, Naruhiro

× Matsufuji, Naruhiro

WEKO 464902

Matsufuji, Naruhiro

Search repository
Toshito, Toshiyuki

× Toshito, Toshiyuki

WEKO 464903

Toshito, Toshiyuki

Search repository
Akagi, Takashi

× Akagi, Takashi

WEKO 464904

Akagi, Takashi

Search repository
Otsuka, Shinya

× Otsuka, Shinya

WEKO 464905

Otsuka, Shinya

Search repository
Shibamoto, Yuta

× Shibamoto, Yuta

WEKO 464906

Shibamoto, Yuta

Search repository
松藤 成弘

× 松藤 成弘

WEKO 464907

en 松藤 成弘

Search repository
赤城 卓

× 赤城 卓

WEKO 464908

en 赤城 卓

Search repository
抄録
内容記述タイプ Abstract
内容記述 We investigated the applicability of the repairable-conditionally repairable (RCR) model and the multi-target (MT) model to dose conversion in high-dose-per-fraction radiotherapy in comparison with the linear-quadratic (LQ) model. Cell survival data of V79 and EMT6 single cells receiving single doses of 2-12 Gy or 2 or 3 fractions of 4 or 5 Gy each, and that of V79 spheroids receiving single doses of 5-26 Gy or 2-5 fractions of 5-12 Gy, were analyzed. Single and fractionated doses to actually reduce cell survival to the same level were determined by a colony assay. Single doses used in the experiments and surviving fractions at the doses were substituted into equations of the RCR, MT and LQ models in the calculation software Mathematica, and each parameter coefficient was computed. Thereafter, using the coefficients and the three models, equivalent single doses for the hypofractionated doses were calculated. They were then compared with actually-determined equivalent single doses for the hypofractionated doses. The equivalent single doses calculated using the RCR, MT and LQ models tended to be lower than the actually determined equivalent single doses. The LQ model seemed to fit relatively well at doses of 5 Gy or less. At 6 Gy or higher doses, the RCR and MT models seemed to be more reliable than the LQ model. In hypofractionated stereotactic radiotherapy, the LQ model should not be used, and conversion models incorporating the concept of the RCR or MT models, such as the generalized linear-quadratic models, appear to be more suitable.
書誌情報 Journal of Radiation Research

巻 54, p. 367-373, 発行日 2012-10
ISSN
収録物識別子タイプ ISSN
収録物識別子 0449-3060
DOI
識別子タイプ DOI
関連識別子 10.1093/jrr/rrs089
戻る
0
views
See details
Views

Versions

Ver.1 2023-05-15 23:49:27.720257
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR 2.0
  • OAI-PMH JPCOAR 1.0
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by WEKO3


Powered by WEKO3