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Radiotherapy for inoperable and refractory endometriosis presenting with massive hemorrhage: a case report
https://repo.qst.go.jp/records/46606
https://repo.qst.go.jp/records/4660648edacb9-b677-43a9-8a6e-cebbe11b5172
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2013-10-17 | |||||
| タイトル | ||||||
| タイトル | Radiotherapy for inoperable and refractory endometriosis presenting with massive hemorrhage: a case report | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Nomiya, Takuma
× Nomiya, Takuma× Harada, Mayumi× Sudo, Hiroko× Ota, Ibuki× Ichikawa, Mayumi× Suzuki, Motohisa× Murakami, Misako× Nemoto, Kenji× 野宮 琢磨× 鈴木 志恒 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | INTRODUCTION: Many patients with endometriosis are treated with medication or by surgical approaches. However, a small number of patients do not respond to medication and are inoperable because of comorbidities. This case report shows the effectiveness of radiotherapy for refractory endometriosis and includes a time series of serum estradiol levels. \nCASE PRESENTATION: A 47-year-old Asian woman presented to our facility with uncontrolled endometriosis refractory to medication. Our patient was considered inoperable because of severe idiopathic thrombocytopenic purpura, and underwent radiotherapy for massive genital bleeding requiring blood transfusions. A radiation dose of 20Gy in 10 fractions was delivered to the pelvis, including the bilateral ovaries, uterus, and myomas. An additional 10Gy in five fractions was delivered to the endometrium to control residual bleeding. Genital bleeding was completely inhibited on day 46 after radiotherapy. Hormonal analysis revealed that radiotherapy induced post-menopausal status. Two years after radiotherapy, atypical genital bleeding had not recurred and has been well controlled without side effects. \nCONCLUSIONS: Disrupted ovarian function is an adverse effect of radiotherapy. However, radiotherapy can be useful for inducing menopause. In cases of medication-refractory or inoperable endometriosis, radiotherapy would be an effective treatment option. |
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| 書誌情報 |
Journal of Medical Case Reports (Online Only URL:http://www.jmedicalcasereports.com/) 巻 6, 号 1, p. 308, 発行日 2012-09 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1752-1947 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1186/1752-1947-6-308. | |||||
