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Roles and limitations of FDG PET in pediatric non-Hodgkin lymphoma.
https://repo.qst.go.jp/records/46588
https://repo.qst.go.jp/records/4658845018d2f-6666-4be1-9282-3889f0851189
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2013-08-28 | |||||
| タイトル | ||||||
| タイトル | Roles and limitations of FDG PET in pediatric non-Hodgkin lymphoma. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Nakatani, Koya
× Nakatani, Koya× Nakamoto, Yuji× Saga, Tsuneo× Higashi, Tatsuya× Togashi, Kaori× et.al× 佐賀 恒夫 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The usefulness of 18F fluorodeoxyglucose (FDG) positron emission tomography (PET) in pediatric Hodgkin lymphoma (p-HL) has been well demonstrated; however, pediatric non-Hodgkin lymphoma (p-NHL) has distinct characteristics from p-HL and adult NHL. We assessed roles of FDG PET in p-NHL. Nineteen patients with p-NHL underwent 80 scans. Scans for staging (group A, n=6) and response assessment (group B, n=42) were compared with conventional imaging modalities (CIMs). Scans within group B for end-chemotherapy assessment (subgroup B+, n=11) and for post-therapeutic surveillance (group C, n=32) were analyzed for diagnostic performance. In group A, PET and CIM demonstrated comparable results. In group B, PET diagnoses were concordant with CIM in 21 and discordant in 11 studies. Of the discordant cases, PET suggested remnant lesions in 5 cases, whereas CIM suggested lesions in 6 cases. PET modified therapeutic strategy in 4 cases by detecting new extranodal lesions. In subgroup B+, sensitivity, specificity, and accuracy for predicting relapse were 50%, 71%, and 64%, respectively. In group C, sensitivity, specificity, and accuracy were 100%, 87%, and 88%, respectively, but positive predictive value was 33%. The role of FDG PET in p-NHL may be limited, unlike with p-HL or adult NHL. Nevertheless, FDG PET may serve complementarily in detecting unexpected lesions that can emerge in p-NHL. |
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| 書誌情報 |
Clinical Nuclear Medicine 巻 37, 号 7, p. 656-662, 発行日 2012-07 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0363-9762 | |||||
