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Four-dimensional Lung Treatment Planning in Layer-stacking Carbon Ion Beam Treatment: Comparison of Layer-stacking and Conventional Ungated/Gated Irradiation
https://repo.qst.go.jp/records/46222
https://repo.qst.go.jp/records/4622276a28a2a-4629-46ca-84a6-7bb15949b682
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2011-12-15 | |||||
| タイトル | ||||||
| タイトル | Four-dimensional Lung Treatment Planning in Layer-stacking Carbon Ion Beam Treatment: Comparison of Layer-stacking and Conventional Ungated/Gated Irradiation | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Mori, Shinichiro
× Mori, Shinichiro× Kanematsu, Nobuyuki× Asakura, Hiroshi× Gregory, Sharp× Kumagai, Motoki× Dobashi, Suguru× Nakajima, Mio× Yamamoto, Naoyoshi× Kandatsu, Susumu× Baba, Masayuki× 森 慎一郎× 兼松 伸幸× 浅倉 裕史× 熊谷 始紀× 土橋 卓× 中嶋 美緒× 山本 直敬× 神立 進× 馬場 雅行 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | PURPOSE: We compared four-dimensional (4D) layer-stacking and conventional carbon ion beam distribution in the treatment of lung cancer between ungated and gated respiratory strategies using 4DCT data sets. \nMETHODS AND MATERIALS: Twenty lung patients underwent 4DCT imaging under free-breathing conditions. Using planning target volumes (PTVs) at respective respiratory phases, two types of compensating bolus were designed, a full single respiratory cycle for the ungated strategy and an approximately 30% duty cycle for the exhalation-gated strategy. Beams were delivered to the PTVs for the ungated and gated strategies, PTV(ungated) and PTV(gated), respectively, which were calculated by combining the respective PTV(Tn)s by layer-stacking and conventional irradiation. Carbon ion beam dose distribution was calculated as a function of respiratory phase by applying a compensating bolus to 4DCT. Accumulated dose distributions were calculated by applying deformable registration. \nRESULTS: With the ungated strategy, accumulated dose distributions were satisfactorily provided to the PTV, with D95 values for layer-stacking and conventional irradiation of 94.0% and 96.2%, respectively. V20 for the lung and Dmax for the spinal cord were lower with layer-stacking than with conventional irradiation, whereas Dmax for the skin (14.1 GyE) was significantly lower (21.9 GyE). In addition, dose conformation to the GTV/PTV with layer-stacking irradiation was better with the gated than with the ungated strategy. \nCONCLUSIONS: Gated layer-stacking irradiation allows the delivery of a carbon ion beam to a moving target without significant degradation of dose conformity or the development of hot spots |
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| 書誌情報 |
International Journal of Radiation Oncology Biology Physics 巻 80, 号 2, p. 597-607, 発行日 2011-06 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0360-3016 | |||||
