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Meta-analysis of non-tumour doses for radiation-induced cancer on the basis of dose-rate
https://repo.qst.go.jp/records/46095
https://repo.qst.go.jp/records/460954348500c-82f8-47de-95c7-9654c09d6eee
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2011-06-06 | |||||
| タイトル | ||||||
| タイトル | Meta-analysis of non-tumour doses for radiation-induced cancer on the basis of dose-rate | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Tanooka, Hiroshi
× Tanooka, Hiroshi× 田ノ岡 宏 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Purpose: Quantitative analysis of cancer risk of ionising radiation as a function of dose-rate. Materials and methods: Non-tumour dose, Dnt, defined as the highest dose of radiation at which no statistically significant tumour increase was observed above the control level, was analysed as a function of dose-rate of radiation. Results: An inverse correlation was found between Dnt and dose-rate of the radiation. Dnt increased 20-fold with decreasing dose-rate from 1–1078 Gy/min for whole body irradiation with low linear energy transfer (LET) radiation. Partial body radiation also showed a dose-rate dependence with a 5- to 10-fold larger Dnt as dose rate decreased. The dose-rate effect was also found for high LET radiation but at 10-fold lower Dnt levels. Conclusions: The cancer risk of ionising radiation varies 1000-fold depending on the dose-rate of radiation and exposure conditions. This analysis explains the discrepancy of cancer risk between A-bomb survivors and radium dial painters. |
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| 書誌情報 |
International Journal of Radiation Biology 巻 87, 号 7, p. 645-652, 発行日 2011-01 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0955-3002 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.3109/09553002.2010.545862 | |||||
