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Malignant mucosal melanoma treated with carbon ion radiotherapy with concurrent chemotherapy: Prognostic value of pretreatment apparent diffusion coefficient (ADC)
https://repo.qst.go.jp/records/46007
https://repo.qst.go.jp/records/4600789f7ba70-f8c0-4d74-9687-756383993c87
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2011-02-25 | |||||
| タイトル | ||||||
| タイトル | Malignant mucosal melanoma treated with carbon ion radiotherapy with concurrent chemotherapy: Prognostic value of pretreatment apparent diffusion coefficient (ADC) | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Jingu, Keiichi
× Jingu, Keiichi× Kishimoto, Riwa× Mizoe, Junetsu× Hasegawa, Azusa× Bessho, Hiroki× Tsuji, Hiroshi× Kamada, Tadashi× Yamada, Syougo× Tsujii, Hirohiko× 神宮 啓一× 岸本 理和× 溝江 純悦× 長谷川 安都佐× 別所 央城× 辻 比呂志× 鎌田 正× 山田 章吾× 辻井 博彦 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background and purpose: To evaluate the potential of apparent diffusion coefficient (ADC) value before carbon ion radiotherapy (C-ion RT) for malignant mucosal melanoma (MMM) to predict prognosis. Materials and methods: We recruited 37 patients with MMM in the head and neck treated by C-ion RT with concomitant chemotherapy. Univariate and multivariate analyses of minimum ADC, mean ADC, tumor volume, age, PS, and gender were performed to identify prognostic factors. Results: The 3-year local control rate, distant metastasis-free survival rate and overall survival rate of all patients were 81.1%, 37.6% and 65.3%, respectively, with a median follow-up period of 19.0 months. In univariate analyses, lower minimum ADC (<=0.6380X10^-3^ mm2/s) and lower mean ADC (<=1.1523X10^-3^ mm2/s) were unfavorable prognostic factors for distant metastasis (p = 0.029 and p = 0.014, respectively), and lower minimum ADC was an unfavorable prognostic factor for overall survival (p = 0.019).However, there was no significant prognostic factor of local control including ADC value. In multivariateanalyses, only minimum ADC was selected as a prognostic factor of distant metastasis-free survival and overall survival (p = 0.015 and p = 0.006, respectively). Conclusion: Minimum ADC can be a prognostic factor of MMM in the head and neck after C-ion RT. |
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| 書誌情報 |
Radiotherapy and Oncology 巻 98, 号 1, p. 68-73, 発行日 2010-10 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0167-8140 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1016/j.radonc.2010.09.017 | |||||
