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Chronic repetitive transcranial magnetic stimulation failed to change dopamine synthesis rate: Preliminary L-[beta-11C]DOPA positron emission tomography study in patients with depression
https://repo.qst.go.jp/records/45966
https://repo.qst.go.jp/records/4596665a75d41-a12a-4866-9fe7-b2fab31c5d08
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2010-12-14 | |||||
| タイトル | ||||||
| タイトル | Chronic repetitive transcranial magnetic stimulation failed to change dopamine synthesis rate: Preliminary L-[beta-11C]DOPA positron emission tomography study in patients with depression | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Kuroda, Yuko
× Kuroda, Yuko× Motohashi, Nobutaka× Ito, Hiroshi× Ito, Shigeo× Takano, Akihiro× Takahashi, Hidehiko× Nishikawa, Touru× Suhara, Tetsuya× 黒田 裕子× 伊藤 浩× 伊藤 滋朗× 高野 晶寛× 高橋 英彦× 須原 哲也 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | We have examined the effects of repetitive transcranial magnetic stimulation (rTMS) on central dopaminergic function in patients with depression using positron emission tomography with L-[beta-11C]DOPA, a ligand to assess the rate of endogenous dopamine synthesis. Eight patients were treated with 10-daily sessions of rTMS over the left dorsolateral prefrontal cortex. Positron emission tomography scanning was performed in each patient twice, before the first session and 1 day after the last session. Although four out of eight patients responded to rTMS, there were no changes in the striatal dopamine synthesis rate (k) following rTMS. These results suggest that chronic rTMS had a limited effect on the dopaminergic system. | |||||
| 書誌情報 |
Psychiatry and Clinical Neurosciences 巻 64, 号 6, p. 659-662, 発行日 2010-10 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1323-1316 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1111/j.1440-1819.2010.02152.x | |||||
