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Morphogenesis of the medaka cerebellum, with special reference to the mesencephalic sheet, a structure homologous to the rostrolateral part of mammalian anterior medullary velum.
https://repo.qst.go.jp/records/45856
https://repo.qst.go.jp/records/45856b7f7bce7-e1a6-4c12-9b65-cbb09eba272a
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2010-07-13 | |||||
| タイトル | ||||||
| タイトル | Morphogenesis of the medaka cerebellum, with special reference to the mesencephalic sheet, a structure homologous to the rostrolateral part of mammalian anterior medullary velum. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Ishikawa, Yuuji
× Ishikawa, Yuuji× et.al× 石川 裕二 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | We have examined cerebellar morphogenesis after neural tube stage in medaka (Oryzias latipes), a ray-finned fish, by conventional histology and immunohistochemistry using anti-proliferating cell nuclear antigen (PCNA) and anti-acetylated tubulin antibodies. Our results indicate that the medaka cerebellum is formed in the four successive stages: 1) formation and enlargement of the cerebellar primordia, 2) rostral midline fusion of the left/right halves of the cerebellar primordia, 3) formation of the cerebellar matrix zones in the midline and caudalmost regions of the primitive cerebellum, and 4) growth and differentiation of the cerebellum. Our results also show that cerebellar morphogenesis is different from that in mammals in three important points: the developmental origins of the primordia, directions along which cerebellar fusion proceeds, and number, locations and duration of the cerebellar matrix zones. During the course of this study, an alar-derived membranous structure between the cerebellum and the midbrain in the adult medaka brain was identified as the structure homologous to the rostrolateral part of the mammalian anterior medullary velum. We have named this structure in the adult teleostean brains as the mesencephalic sheet. The present study indicates that there exist both conserved and divergent patterns in cerebellar morphogenesis in vertebrates. | |||||
| 書誌情報 |
Brain, Behavior and Evolution 巻 75, 号 2, p. 88-103, 発行日 2010-06 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0006-8977 | |||||
