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A Small animal holding fixture system with positional reproducibility for longitudinal multimodal imaging
https://repo.qst.go.jp/records/45847
https://repo.qst.go.jp/records/458477470354e-6f8b-4418-b083-d04a245a9af6
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2010-07-08 | |||||
| タイトル | ||||||
| タイトル | A Small animal holding fixture system with positional reproducibility for longitudinal multimodal imaging | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Kokuryo, Daisuke
× Kokuryo, Daisuke× Kimura, Yuichi× Obata, Takayuki× Yamaya, Taiga× Kawamura, Kazunori× Zhang, Ming-Rong× Kanno, Iwao× Aoki, Ichio× 國領 大介× 木村 裕一× 小畠 隆行× 山谷 泰賀× 河村 和紀× 張 明栄× 菅野 巖× 青木 伊知男 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | This study presents a combined small animal holding fixture system, termed a 'bridge capsule', which provides for small animal re-fixation with positional reproducibility. This system comprises separate holding fixtures for the head and lower body and a connecting part to a gas anesthesia system. A mouse is fixed in place by the combination of a head fixture with a movable part made from polyacetal resin, a lower body fixture made from vinyl-silicone and a holder for the legs and tail. For re-fixation, a similar posture could be maintained by the same holding fixtures and a constant distance between the head and lower body fixtures is maintained. Artifacts caused by the bridge capsule system were not observed on magnetic resonance (MRI) and positron emission tomography (PET) images. The average position differences of the spinal column and the iliac body before and after re-fixation for the same modality were approximately 1.1 mm. The difference between the MRI and PET images was approximately 1.8 mm for the lower body fixture after image registration using fiducial markers. This system would be useful for longitudinal, repeated and multimodal imaging experiments requiring similar animal postures. | |||||
| 書誌情報 |
Physics in Medicine and Biology 巻 55, 号 14, p. 4119-4130, 発行日 2010-07 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0031-9155 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1088/0031-9155/55/14/011 | |||||
