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mRNA expression of a cadmium-responsive gene is a sensitive biomarker of cadmium exposure in the soil collembolan Folsomia candida
https://repo.qst.go.jp/records/45786
https://repo.qst.go.jp/records/4578660795775-935a-4b19-a4c6-e004a6d3825e
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2010-04-16 | |||||
タイトル | ||||||
タイトル | mRNA expression of a cadmium-responsive gene is a sensitive biomarker of cadmium exposure in the soil collembolan Folsomia candida | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Nakamori, Taizo
× Nakamori, Taizo× Fujimori, Akira× Kinoshita, Keiji× Ban-nai, Tadaaki× Kubota, Yoshihisa× Yoshida, Satoshi× 中森 泰三× 藤森 亮× 坂内 忠明× 久保田 善久× 吉田 聡 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The gene expression of environmental organisms is useful as a biomarker of environmental pollution. One of its advantages is high sensitivity. We identified the cDNA of a novel cadmium-responsive gene in the soil collembolan Folsomia candida. The deduced protein, designated "metallothionein-like motif containing protein" (MTC), was cysteine-rich and contained a metallothionein-like motif with similarity to metallothionein, bat had a much longer sequence than metallothionein and contained repeated sequences of amino acids. Expression of MTC mRNA was sensitively induced by cadmium exposure at 0.3 mg/kg of dry food, a concentration at which toxic effects are not observed, but expression was not affected by #-ray exposure (an inducer of oxidative stress). These findings suggest that MTC is involved in cadmium-binding processes rather than in oxidative stress responses. In conclusion, we suggest that gene expression of MTC may be a candidate biomarker for detecting low levels of cadmium contamination in soil. | |||||
書誌情報 |
Environmental Pollution 巻 158, 号 5, p. 1689-1695, 発行日 2010-05 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0269-7491 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.envpol.2009.11.022 |