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Dose Thioredoxin-1 Prevent Mitochondria- and Endoplasmic Reticulum-Mediated Neurotoxicity of 1-Methyl-4-phenyl-1,2,3,6-Tetrahydropyridine?
https://repo.qst.go.jp/records/45639
https://repo.qst.go.jp/records/456390dc96e5a-af9f-46fd-9ac9-d4697ffa7184
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2009-09-15 | |||||
| タイトル | ||||||
| タイトル | Dose Thioredoxin-1 Prevent Mitochondria- and Endoplasmic Reticulum-Mediated Neurotoxicity of 1-Methyl-4-phenyl-1,2,3,6-Tetrahydropyridine? | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Jie, Bai
× Jie, Bai× Ban, Sadayuki× et.al× 伴 貞幸 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | We show that 1-methyl-4-phenylpyridinium ion(MPP+), and active metabolite of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP),induces cytotoxicity via endoplasmic reticulum(ER)-and mitochondria-mediated pathways, and thioredoxin-1(TRX-1), a redox-active protein, prevents MPTP-induced neurotoxicity. | |||||
| 書誌情報 |
Antioxidants & Redox Signaling 巻 9, 号 5, p. 603-608, 発行日 2007-05 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1523-0864 | |||||
