WEKO3
アイテム
D1 dopamine receptor binding in mood disorders measured by positron emission tomography
https://repo.qst.go.jp/records/45430
https://repo.qst.go.jp/records/4543096d1bec2-9b46-4e10-8736-f0ee19218268
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2009-02-25 | |||||
| タイトル | ||||||
| タイトル | D1 dopamine receptor binding in mood disorders measured by positron emission tomography | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Suhara, Tetsuya
× Suhara, Tetsuya× Inoue, Osamu× Fukuda, Hiroshi× Tateno, Yukio× et.al× 須原 哲也× 井上 修× 福田 寛× 舘野 之男 |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | D1 dopamine receptor binding in mood disorders was studied by positron emission tomography (PET) using11C-SCH23390. Ten patients with bipolar mood disorders and 21 normal controls were studied in the drug-free state. The patients were in euthymic (N=6), depressed (N=3) and manic (N=1) states. Regional radioactivity in the brain was followed for 40 min by PET. A two-compartment model was used to obtain the binding potential (k3/k4) for the striatum and frontal cortex. The binding potentials for the frontal cortex for the patients were significantly lower than those for normal controls, whereas those for striatum were not significantly different. These findings suggest that D1 dopamine receptors in the frontal cortex may be in a different state in patients with bipolar mood disorders. | |||||
| 書誌情報 |
Psychopharmacology 巻 106, p. 14-18, 発行日 1992-01 |
|||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0033-3158 | |||||
