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Microdosimetric evaluation of secondary particles in a phantom produced by carbon 290 MeV/nucleon ions at HIMAC
https://repo.qst.go.jp/records/45181
https://repo.qst.go.jp/records/451811d3bc4a7-76c3-4032-976e-01f4f29cd75d
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2008-06-10 | |||||
タイトル | ||||||
タイトル | Microdosimetric evaluation of secondary particles in a phantom produced by carbon 290 MeV/nucleon ions at HIMAC | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Endo, Satoru
× Endo, Satoru× Takada, Masashi× Onizuka, Yoshihiko× Tanaka, Ken-ichi× Maeda, Naoko× Miyahara, Nobuyuki× Hayabuchi, Naofumi× Shizuma, Kiyoshi× Hoshi, Masaharu× et.al× 遠藤 暁× 高田 真志× 鬼塚 昌彦× 田中 憲一× 前田 直子× 宮原 信幸× 早渕 尚文× 静間 清× 星 正治 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Microdosimetric single event spectra as a function of depth in a phantom for the 290 MeV/nucleon therapeutic carbon beam at HIMAC were measured by using a tissue equivalent proportional counter (TEPC). Two types of geometries were used: one is a fragment particle identification measurement (PID-mode) with time of flight (TOF) method without a backward phantom, and the other is an in-phantom measurement (IPM-mode) with a backward phantom. On the PID-mode geometry, fragments produced by carbon beam in a phantom are identified by the deltaE-TOF distribution between two scintillation counters positioned up- and down-stream relative to the tissue equivalent proportional counter (TEPC). Lineal energy distributions for carbon and five ion fragments (proton, helium, lithium, beryllium and boron) were obtained in the lineal-energy range of 0.1-1000 keV/um at eight depths (7.9-147.9 mm) in an acrylic phantom. In the IPM-mode geometry, the total lineal energy distributions measured at eight depths (61.9-322.9 mm) were compared with the distributions in the PID-mode. Both spectra are consistent with each other. This shows that the PID-mode measurement can be discussed as the equivalent of the phantom measurement. The dose distribution of the carbon beam and fragments were obtained separately. In the depth dose curve, the Bragg peak was observed. Relative biological effectiveness (RBE) for the carbon beam in the acrylic phantom was obtained based on a biological response function as a lineal-energy. The RBE of carbon beam had a maximum of 4.5 at the Bragg peak. Downstream of the Bragg peak, the RBE rapidly decreases. The RBE of fragments is dominated by Boron particles around the Bragg peak region. |
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書誌情報 |
Journal of Radiation Research 巻 48, 号 5, p. 397-406, 発行日 2007 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0449-3060 |