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A practical route for synthesizing a PET ligand containing [18F]fluorobenzene using reaction of diphenyliodonium salt with [18F]F-
https://repo.qst.go.jp/records/45019
https://repo.qst.go.jp/records/450198fb71d49-2e37-4776-8fbb-4f8afe3f0bba
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2007-11-12 | |||||
タイトル | ||||||
タイトル | A practical route for synthesizing a PET ligand containing [18F]fluorobenzene using reaction of diphenyliodonium salt with [18F]F- | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Zhang, Ming-Rong
× Zhang, Ming-Rong× Kumata, Katsushi× Suzuki, Kazutoshi× 張 明栄× 熊田 勝志× 鈴木 和年 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The aim of this study was to develop a practical route for preparing a fluorine-18 ([18F]) labelled ligand ([18F]1) containing [18F]fluorobenzene ring by employing the reaction of diphenyliodonium salt with [18F]F−. Diphenyliodonium tosylate (2) was synthesized from tributylphenylstannyl compound (6) with [hydroxy(tosyloxy)iodo]benzene (7). Using this method, [18F]DAA1106 ([18F]3a), a positron emission tomography ligand for imaging peripheral-type benzodiazepine receptor, was prepared. | |||||
書誌情報 |
Tetrahedron Letters 巻 48, 号 49, p. 8632-8635, 発行日 2007-11 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0040-4039 |