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Dopamine D1 receptors in Parkinson's disease and striatonigral degeneration: a positron emission tomography study
https://repo.qst.go.jp/records/44469
https://repo.qst.go.jp/records/4446978162a3c-726a-4078-92e1-b5e641e7a878
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2006-07-18 | |||||
| タイトル | ||||||
| タイトル | Dopamine D1 receptors in Parkinson's disease and striatonigral degeneration: a positron emission tomography study | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Shinoto, Hitoshi
× Shinoto, Hitoshi× Inoue, Osamu× Suhara, Tetsuya× Tateno, Yukio× et.al× 篠遠 仁× 井上 修× 須原 哲也× 舘野 之男 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Striatal dopamine D1 receptors were investigated in 11 patients with Parkinson's disease (PD), five patients with striatonigral degeneration (SND) and six age-matched controls by positron emission tomography and carbon-11 labelled SCH23390. The SND patients showed mean 12%, 21% and 31% declines in the ratios of radioactivity in the caudate, anterior putamen, and posterior putamen compared with that in the occipital cortex. These ratios were not significantly altered in the PD patients. The results may explain the different therapeutic responses to levadopa between SND and PD patients, and this technique might prove useful for their differentiation. | |||||
| 書誌情報 |
Journal of Neurology, Neurosurgery, and Psychiatry 巻 56, p. 467-472, 発行日 1993 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0022-3050 | |||||
