WEKO3
アイテム
Human hepatic carbohydrate metabolism. Dynamic observation using 13C MRS without proton decoupling.
https://repo.qst.go.jp/records/44374
https://repo.qst.go.jp/records/44374d91ad852-4db9-43d7-8882-57b9c128c347
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2006-06-29 | |||||
| タイトル | ||||||
| タイトル | Human hepatic carbohydrate metabolism. Dynamic observation using 13C MRS without proton decoupling. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Ikehira, Hiroo
× Ikehira, Hiroo× Obata, Takayuki× Koga, Masahisa× Yoshida, Katsuya× 池平 博夫× 小畠 隆行× 古賀 雅久× 吉田 勝哉 |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | PURPOSE: Dynamic natural-abundance 13C MR spectroscopy (MRS) studies without proton decoupling were performed in the human liver using commercial 1.5 T MR equipment. MATERIAL AND METHODS: A single tuned custom-made circular surface coil with an OD of 20 cm operating at 16.04 MHz was used for the 13C study. Seventy-five grams of glucose dissolved in water was administered for the natural-abundance 13C-MRS dynamic study which lasted for approximately 40 to 60 min. Data acquisition was broken into 20-min and 1.7-min blocks. Localized proton shimming with a whole-body coil was performed with sufficient volume to include the observing area of the surface coil; the line width of the water signal was less than 20 Hz. RESULTS AND CONCLUSION: The glucose and glycogen spectra were clearly visible at 80 to 120 ppm after oral administration of the glucose solution. These data demonstrate that dynamic hepatic carbohydrate metabolism can be observed with commercially available MR equipment. Given that the human hepatic glycogen pool reaches maximum level within less than 10 min, this technique should provide a direct diagnosis of hepatic carbohydrate metabolic disorders. | |||||
| 書誌情報 |
Acta Radiologica 巻 38, 号 6, p. 998-1002, 発行日 1997-11 |
|||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0284-1851 | |||||
