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Dynamic human glycogen and glucose metabolism detection utilizing in vivo 13C NMR.
https://repo.qst.go.jp/records/43976
https://repo.qst.go.jp/records/43976d00b8388-ef48-4630-a848-2c4962f8d9e5
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2006-01-31 | |||||
タイトル | ||||||
タイトル | Dynamic human glycogen and glucose metabolism detection utilizing in vivo 13C NMR. | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Ikehira, Hiroo
× Ikehira, Hiroo× et.al× 池平 博夫 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The dynamic detection studies of glucose-glycogen metabolism of the human liver were performed with normal volunteers. A single tuned surface coil of 20-cm diameter was used for 13C (at 16.04 MHz). Natural glucose 100 g was administered for the natural abundance 13C MR dynamic study and 13C enriched (99%) 1-13C-D-glucose 1 g mixed 75 g glucose was administered to study the 13C enrichment effect. The total scan time of this dynamic study was 1 hr and each single scan time was 20 min. We did not use proton decoupling for the human 13C MR study. Localized (PRIME) proton shimming was performed and the shim value was less than 20 Hz. Glucose and glycogen spectra were clearly visible at 120 to 80 ppm and about 3 hr later both peaks almost disappeared. These data demonstrate that dynamic hepatic glucose-glycogen metabolism should be possible to detect which should allow for the direct diagnosis of hepatic glucose-glycogen metabolic disorders. | |||||
書誌情報 |
American Journal of Physiologic Imaging 巻 7, 号 1, p. 32-35, 発行日 1992-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0885-8276 |