ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

  1. 原著論文

Dimerization and DNA binding facilitate alpha-helix formation of Max in solution.

https://repo.qst.go.jp/records/43927
https://repo.qst.go.jp/records/43927
62accca0-c239-4dfb-8bce-85fead77d097
Item type 学術雑誌論文 / Journal Article(1)
公開日 2005-12-16
タイトル
タイトル Dimerization and DNA binding facilitate alpha-helix formation of Max in solution.
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Kurihara, Yasuyuki

× Kurihara, Yasuyuki

WEKO 436701

Kurihara, Yasuyuki

Search repository
Katahira, Masato

× Katahira, Masato

WEKO 436702

Katahira, Masato

Search repository
Saito, Toshiyuki

× Saito, Toshiyuki

WEKO 436703

Saito, Toshiyuki

Search repository
Uesugi, Seiichi

× Uesugi, Seiichi

WEKO 436704

Uesugi, Seiichi

Search repository
et.al

× et.al

WEKO 436705

et.al

Search repository
齋藤 俊行

× 齋藤 俊行

WEKO 436706

en 齋藤 俊行

Search repository
抄録
内容記述タイプ Abstract
内容記述 Max is a basic region/helix-loop-helix/leucine zipper (b/HLH/Z) protein that forms a hetero-complex with the Myc family proteins Myc, Mad, and Mxi1, and a homo-complex with itself. These complexes specifically bind to double-stranded DNA containing CACGTG sequences. Here, we report on the structural properties in aqueous solution of a 109-amino-acid protein, Max110, corresponding to the N-terminal domain of Max containing the b/HLH/Z motif (residues 2-110), as characterized by combined use of circular dichroism (CD) and sedimentation equilibrium experiments. The results showed that the alpha-helical content of Max110 increases with increasing protein concentration. The sedimentation equilibrium data indicated that Max110 exists as a monomer at low protein concentration, and forms a dimer at high protein concentration. Further increases in the alpha-helical content of Max110 occur upon addition of DNA with the CACGTG recognition sequence. Thus, dimerization and binding to DNA of Max both favor an increase of the alpha-helical content.
書誌情報 Journal of Biochemistry

巻 122, p. 711-716, 発行日 1997-10
ISSN
収録物識別子タイプ ISSN
収録物識別子 0021-924X
戻る
0
views
See details
Views

Versions

Ver.1 2023-05-16 00:21:26.498722
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR 2.0
  • OAI-PMH JPCOAR 1.0
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by WEKO3


Powered by WEKO3