WEKO3
アイテム
Isolation and chromosomal assignment of human genes encoding cofactor of LIM homeodomain proteins, CLIM1 and CLIM2.
https://repo.qst.go.jp/records/43903
https://repo.qst.go.jp/records/43903256939f0-2060-4cc0-90fa-ccef84c2e58f
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2005-12-16 | |||||
| タイトル | ||||||
| タイトル | Isolation and chromosomal assignment of human genes encoding cofactor of LIM homeodomain proteins, CLIM1 and CLIM2. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Ueki, Nobuhide
× Ueki, Nobuhide× Seki, Naohiko× Yano, Kazuhiro× Ohira, Miki× Saito, Toshiyuki× Masuho, Yasuhiko× Muramatsu, Masa-aki× 関 直彦× 齋藤 俊行 |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Cofactors of LIM homeodomain proteins (CLIM) are transcriptional activators that associate with the LIM homeoproteins and coordinate transcription. LIM homeoproteins and CLIMs are involved in a variety of developmental processes. Two CLIMs, CLIM1 and CLIM2, have been identified in the mouse. Here we report the isolation of human CLIM1 and CLIM2 cDNAs and the determination of their chromosome locations by using a human-rodent monochromosomal hybrid cell panel and a radiation hybrid mapping panel. The proteins deduced from human CLIM1 and CLIM2 cDNAs were composed of 373 and 375 amino acids, respectively, and had 97.3% and 98.7% amino acid identity, respectively, to their mouse counterparts. Human CLIM1 and CLIM2 proteins were 75.5% identical. Human CLIM1 and CLIM2 genes were mapped to the chromosome on 4p15.3 and 10q24-q25 regions, respectively. Mapping of a pair of developmentally important genes may provide new clues to the understanding of genetic disorders caused by these chromosome regions. | |||||
| 書誌情報 |
Journal of Human Genetics 巻 44, p. 112-115, 発行日 1999-03 |
|||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1434-5161 | |||||
