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Neonate showing a reversible splenial lesion
https://repo.qst.go.jp/records/43869
https://repo.qst.go.jp/records/438697bb98a01-cb6f-40d3-800b-85ebb24601b4
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2005-12-12 | |||||
| タイトル | ||||||
| タイトル | Neonate showing a reversible splenial lesion | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Takanashi, Junichi
× Takanashi, Junichi× et.al× 高梨 潤一 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | We read with interest the report of patients with splenium of corpus callosum (SCC) lesions, most being reversible with transiently reduced apparent diffusion coefficient (ADC) values. We previously described 15 patients with clinically mild encephalitis/encephalopathy with identical reversible SCC lesions,2 and we postulated that intramyelinic edema due to separation of myelin layers was a possible mechanism for the transiently decreased ADC. We recently saw a neonate with an identical SCC lesion, suggesting that the mechanism underlying the lesion might not be related to myelination. Magnetic resonance imaging in this neonatal patient revealed an identical reversibleSCClesion with a transiently reducedADCvalue. Pathologically, no myelination ofSCC occurs before age2months. Therefore, intramyelinicedema cannot occur in the neonatal period and is unlikely to be a possible mechanism underlying the reversible SCC lesion in the present patient. Another possible explanation is inflammatory infiltrate.Adiffusion-weighted image study of multiple sclerosis revealed decreased ADC values in some lesions from multiple sclerosis, and it was postulated that the influx of inflammatory cells and macromolecules might have caused the decreased ADC values. A decreased ADC value inSCCmaybe a result of inflammation, and theADC may return to normal if the cause resolves quickly. |
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| 書誌情報 |
Archives of Neurology 巻 62, p. 1481-1482, 発行日 2005 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0003-9942 | |||||
