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  1. 原著論文

Therapeutic purpose 9C beams produced in the secondary beam line at HIMAC

https://repo.qst.go.jp/records/43798
https://repo.qst.go.jp/records/43798
6bd85636-b09e-412b-8fe0-4c9bba656953
Item type 学術雑誌論文 / Journal Article(1)
公開日 2005-09-13
タイトル
タイトル Therapeutic purpose 9C beams produced in the secondary beam line at HIMAC
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Li, Qiang

× Li, Qiang

WEKO 435438

Li, Qiang

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Kitagawa, Atsushi

× Kitagawa, Atsushi

WEKO 435439

Kitagawa, Atsushi

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Kanai, Tatsuaki

× Kanai, Tatsuaki

WEKO 435440

Kanai, Tatsuaki

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Kanazawa, Mitsutaka

× Kanazawa, Mitsutaka

WEKO 435441

Kanazawa, Mitsutaka

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Urakabe, Eriko

× Urakabe, Eriko

WEKO 435442

Urakabe, Eriko

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Tomitani, Takehiro

× Tomitani, Takehiro

WEKO 435443

Tomitani, Takehiro

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Satou, Shinji

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WEKO 435444

Satou, Shinji

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Zhang, Wei

× Zhang, Wei

WEKO 435445

Zhang, Wei

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李 強

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WEKO 435446

en 李 強

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北川 敦志

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WEKO 435447

en 北川 敦志

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金井 達明

× 金井 達明

WEKO 435448

en 金井 達明

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金澤 光隆

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WEKO 435449

en 金澤 光隆

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新谷 恵理子

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WEKO 435450

en 新谷 恵理子

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富谷 武浩

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WEKO 435451

en 富谷 武浩

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佐藤 眞二

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WEKO 435452

en 佐藤 眞二

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張 偉

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WEKO 435453

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抄録
内容記述タイプ Abstract
内容記述 Due to the favorable characteristics of heavy-ion beams such as dose localization as well as high relative biological effectiveness, heavy-ion cancer therapy is attracting growing interests all over the world. The application of beta-delayed particle decay beams like 9C ions in cancer therapy is expected to further improve the treatment efficacy of the modality of heavy-ions. For the first time 9C beams were produced in the secondary beam line (SBL) of the HIMAC facility with a primary 12C beam of 430 MeV/n. The production conditions providing a 9C beam with higher production rate and purity were optimized using different thick production targets and degraders. The results show setting the momentum acceptance to the full value of 5% the production rate is 9.07 x 10^-6^ and the purity is 82.88% for the produced 9C beam under the optimal condition. Because of the large momentum spread for a secondary beam, the momentum distribution of the produced 9C beam at the optimal condition was measured. The momentum among the beam had a nearly Gaussian profile with a standard deviation of 26.1 MeV/c/n and the largest component of the momenta appeared around 838.9 MeV/c/n. In order to form a relatively large uniform irradiation field being apppropriate to further biologicl experiments for the produced 9C beam, the scanning magnets in the irradiation system of the SBL, operating in a wobbling mode, was use. A uniform irradiation field of 20 mm in diameter could be achieved with homogeneity of 93.3%. The work presented in this paper provides a substantial basis for the further studies with 9C beams for the therapeutic purpose.
書誌情報 Nuclear Instruments & Methods in Physics Research Section B

巻 222, p. 270-284, 発行日 2004
ISSN
収録物識別子タイプ ISSN
収録物識別子 0168-583X
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