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Therapeutic purpose 9C beams produced in the secondary beam line at HIMAC
https://repo.qst.go.jp/records/43798
https://repo.qst.go.jp/records/437986bd85636-b09e-412b-8fe0-4c9bba656953
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2005-09-13 | |||||
タイトル | ||||||
タイトル | Therapeutic purpose 9C beams produced in the secondary beam line at HIMAC | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Li, Qiang
× Li, Qiang× Kitagawa, Atsushi× Kanai, Tatsuaki× Kanazawa, Mitsutaka× Urakabe, Eriko× Tomitani, Takehiro× Satou, Shinji× Zhang, Wei× 李 強× 北川 敦志× 金井 達明× 金澤 光隆× 新谷 恵理子× 富谷 武浩× 佐藤 眞二× 張 偉 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Due to the favorable characteristics of heavy-ion beams such as dose localization as well as high relative biological effectiveness, heavy-ion cancer therapy is attracting growing interests all over the world. The application of beta-delayed particle decay beams like 9C ions in cancer therapy is expected to further improve the treatment efficacy of the modality of heavy-ions. For the first time 9C beams were produced in the secondary beam line (SBL) of the HIMAC facility with a primary 12C beam of 430 MeV/n. The production conditions providing a 9C beam with higher production rate and purity were optimized using different thick production targets and degraders. The results show setting the momentum acceptance to the full value of 5% the production rate is 9.07 x 10^-6^ and the purity is 82.88% for the produced 9C beam under the optimal condition. Because of the large momentum spread for a secondary beam, the momentum distribution of the produced 9C beam at the optimal condition was measured. The momentum among the beam had a nearly Gaussian profile with a standard deviation of 26.1 MeV/c/n and the largest component of the momenta appeared around 838.9 MeV/c/n. In order to form a relatively large uniform irradiation field being apppropriate to further biologicl experiments for the produced 9C beam, the scanning magnets in the irradiation system of the SBL, operating in a wobbling mode, was use. A uniform irradiation field of 20 mm in diameter could be achieved with homogeneity of 93.3%. The work presented in this paper provides a substantial basis for the further studies with 9C beams for the therapeutic purpose. | |||||
書誌情報 |
Nuclear Instruments & Methods in Physics Research Section B 巻 222, p. 270-284, 発行日 2004 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0168-583X |