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Genomic Organization and Developmental Expression of Globin Genes in the Teleost Oryzias latipes
https://repo.qst.go.jp/records/43797
https://repo.qst.go.jp/records/437978bde0558-c409-495e-ba68-9caaa1e95fdc
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2005-09-13 | |||||
| タイトル | ||||||
| タイトル | Genomic Organization and Developmental Expression of Globin Genes in the Teleost Oryzias latipes | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Maruyama, Kouichi
× Maruyama, Kouichi× Yasumasu, Shigeki× Naruse, Kiyoshi× Mitani, Takashi× Shima, Akihiro× Iuchi, Ichiro× 丸山 耕一× 安増 茂樹 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | We isolated globin genes from a genomic DNA library of the drR strain of medaka Oryzias latipes, and walked on chromosome. The present study is the first demonstration of the full-length structure of globin gene locus in the teleosts. Two gene clusters were found. One cluster of 36Kbps consisted of nine globin genes and two pseudogenes. Based on structural and phylogenetic similarity of amino acid sequences, the cluster was named embryonic globin gene cluster (E1). The orientation of the genes was in 5'a03'-3'b15'-5'a13'-5'b23'-5'a23'-3'a35'-5'b33'-3'b45'-5'a43'-3'ya5'-5'yb3'. The other cluster of 20Kbps contained three globin genes (3'ad.a15'-5'ad.b13'-3'ad.a25'), and was named adult globin gene cluster (A1). Genetic linkage analysis clarified that E1 and A1 were mapped on linkage group 8 and 19, respectively. The E1 cluster included other genes homologous to human EST clone KIAA0172, Sushi-1 retrotransposon, and protein 14 gene-like gene, while the A1 cluster linked to aquaporin-8 gene-like gene. The expression patterns of the genes were classified into four types: embryo-specific expression (a3, b3, a4 and b4), expression in embryo to young fish (a0, b1, a1 and ad.a2), expression in young to adult fish (a2 and ad.a1) and successive expression in embryo to adult (ad.b1). | |||||
| 書誌情報 |
Gene 巻 335, p. 89-100, 発行日 2004-06 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0378-1119 | |||||
