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Prenatal Low-dose X-irradiation Affects Connexins 43 and 26 in Developing Mouse Neocortex
https://repo.qst.go.jp/records/43787
https://repo.qst.go.jp/records/43787660af9ca-d0de-4c55-b8fa-640f7d8bb125
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2005-08-30 | |||||
| タイトル | ||||||
| タイトル | Prenatal Low-dose X-irradiation Affects Connexins 43 and 26 in Developing Mouse Neocortex | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Yaoi, Takeshi
× Yaoi, Takeshi× Nojima, Kumie× Fushiki, Shinji× et.al× 矢追 毅× 野島 久美恵× 伏木 信次 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | To investigate the effects of low-dose X-irradiation on the expression of connexing(Cxs) in developing cerebral cortex, C57/BL6 pregnant mice were exposed to whole body irradiation of 0.1 Gy and 0.5Gy, on embryonic day 14.5 Fetal telencephalons, at 1,3,12 and 24 hr after exposure, were studied immunohistochemically using anti-Cx43 and Cx26 antibodies, followed by quantitative image analyses. Cx43 expression was significantly reduced in all zones of developing cerebal cortex antil 12hr after exposure,and tended to recover to control level after 24 hr. Cx26 expression was also suppressed in the ventricular zone and cortical p;ate after irradiation, although it recovered much earlier. Our observations indicate that the expression of Cxs is affected by ionizing radiation during cortical histogenesis. | |||||
| 書誌情報 |
Acta Histochemica et Cytochemica 巻 38, 号 3, p. 223-228, 発行日 2005-08 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0044-5991 | |||||
