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Early growth of experimental lung metastasis in mouse
https://repo.qst.go.jp/records/43731
https://repo.qst.go.jp/records/437310634906b-75d2-42fa-81e8-a80242140646
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2005-07-13 | |||||
| タイトル | ||||||
| タイトル | Early growth of experimental lung metastasis in mouse | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Ando, Koichi
× Ando, Koichi× Koike, Sachiko× et.al× 安藤 興一× 小池 幸子 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | A radiobiological method was developed to measure the initial growth of clonogenic tumor cells metastasizing to lung. Thorax of mice was externally irradiated by gamma rays after an intravenous transplantation of syngeneic fibrosarcoma cells. Lung colonies developed 11 days after irradiation were counted and provided surviving fractions. Survival curves moved downward when time interval between transplantation and radiation delayed from 1 to 21 hr, but shifted upward at 48 hr or later. Survival ratios at given doses and the extrapolation number of survival curves fitted to multi-target model were calculated, and plotted against time after the intravenous transplantation. Doubling times of 13.3 and 13.1 hr were obtained by use of the survival ratio and of the extrapolation number, respectively. This method is useful to measure growth dynamics of clonogenic tumor cells at the site of metastasized organ. | |||||
| 書誌情報 |
Journal of Radiation Research 巻 46, 号 1, p. 289-292, 発行日 2005-06 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0449-3060 | |||||
