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  1. 原著論文

Temporal Parenteral Nutrition in Children Causing T1 Shortening in the Anterior Pituitary Gland and Globus Pallidus

https://repo.qst.go.jp/records/43351
https://repo.qst.go.jp/records/43351
04ccaa86-691b-4811-af1f-aed6f3ef7640
Item type 学術雑誌論文 / Journal Article(1)
公開日 2004-02-10
タイトル
タイトル Temporal Parenteral Nutrition in Children Causing T1 Shortening in the Anterior Pituitary Gland and Globus Pallidus
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Suzuki, Hiroko

× Suzuki, Hiroko

WEKO 431231

Suzuki, Hiroko

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Takanashi, Junichi

× Takanashi, Junichi

WEKO 431232

Takanashi, Junichi

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et.al

× et.al

WEKO 431233

et.al

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多田 弘子

× 多田 弘子

WEKO 431234

en 多田 弘子

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高梨 潤一

× 高梨 潤一

WEKO 431235

en 高梨 潤一

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内容記述タイプ Abstract
内容記述 Patients receiving long-term parenteral nutrition (PN) with trace elements (TE) may exhibit T1 shortening in the anterior pituitary gland and basal ganglia. The purposes of this study were to clarify at what time or from what site the signal change begins in children. Retrospective analysis of magnetic resonace imaging results was performed for 10 pediatric patients aged from 1 to 16 years receiving temporal PN, eight of which received PN with TE for less than two months, and 13 patients with headache or seizures as age-matched controls. Axial and sagittal T1-weighted images were obtained to analyze the T1 shortening in the anterior pituitary gland and globus pallidus. All eight patients receiveing PN with TE exhibited T1 shortening in the anterior pituitary gland (six patients) and/or globus pallidus (five patients). No T1 shortening was observed in the other two patients without TE, or the 13 age-matched controls. Therefore, the signal change may be associated with TE administration, and begins markedly earlier than previously reported. We discussed the possibility that manganese (Mn) caused the signal change, and proposed that the administration of a lower dose of Mn is recommended, even in the case of temporal PN, to prevent possible Mn toxicity toward both the brain and liver.
書誌情報 Neuropediatrics

巻 34, p. 200-204, 発行日 2003
ISSN
収録物識別子タイプ ISSN
収録物識別子 0174-304X
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