WEKO3
アイテム
Cytogenetical dose estimation for 3 severely exposed patients in the JCO criticality accident in Tokai-mura.
https://repo.qst.go.jp/records/43183
https://repo.qst.go.jp/records/43183edfaafc6-5958-4d2b-a9c2-4402d2921167
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2003-10-20 | |||||
| タイトル | ||||||
| タイトル | Cytogenetical dose estimation for 3 severely exposed patients in the JCO criticality accident in Tokai-mura. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Hayata, Isamu
× Hayata, Isamu× Kanda, Reiko× Minamihisamatsu, Masako× Furukawa, Akira× Sasaki, Masao× 早田 勇× 神田 玲子× 南久松 眞子× 古川 章× 佐々木 正夫 |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | A dose estimation by chromosome analysis was performed on the 3 severely exposed patients in the Tokai-mura criticality accident. Drastically reduced lymphocyte counts suggested that the whole-body dose of radiation which they had been exposed to was unprecedentedly high. Because the number of lymphocytes in the white blood cells in two patients was very low, we could not culture and harvest cells by the conventional method. To collect the number of lymphocytes necessary for chromosome preparation, we processed blood samples by a modified method, called the high-yield chromosome preparation method. With this technique, we could culture and harvest cells, and then make air-dried chromosome slides. We applied a new dose-estimation method involving an artificially induced prematurely condensed ring chromosome, the PCC-ring method, to estimate an unusually high dose with a short time. The estimated doses by the PCC-ring method were in fairly good accordance with those by the conventional dicentric and ring chromosome (Dic+R) method. The biologically estimated dose was comparable with that estimated by a physical method. As far as we know, the estimated dose of the most severely exposed patient in the present study is the highest recorded among that chromosome analyses have been able to estimate in humans. | |||||
| 書誌情報 |
Journal of Radiation Research 巻 42, 号 Suppl., p. S149-S155, 発行日 2001-09 |
|||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0449-3060 | |||||
