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Expression of receptor for ecotropic murine leukemia virus on hematopoietic cells
https://repo.qst.go.jp/records/43143
https://repo.qst.go.jp/records/431431b8ee7fb-8b28-49a2-bec7-4655785178ca
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2003-09-02 | |||||
| タイトル | ||||||
| タイトル | Expression of receptor for ecotropic murine leukemia virus on hematopoietic cells | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Suzuki, Takako
× Suzuki, Takako× Aizawa, Shirou× Ikeda, Hidetoshi× 相澤 志郎 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | A fusion protein (F-SU/GFP) which is comprised of the surface (SU) subunit of the Friend MuLV envelop glycoprotein and the green fluorescence protein (GFP) was generated by a baculovirus expression system. The F-SU/GFP specifically bound to mammalian tissue cultured cells expressing the mCAT-1, the receptor for ecotropic murine leukemia virus (Eco-MuLV). The expression level of mCAT-1 on hematopoietic cells as measured based on the capacity of cells to absorb the F-SU/GFP. In BALB/c mice susceptible to Eco-MuLV infection, all hematopoietic cell subpopulations absorbed the F-SU/GFP ith the most prominent absorption observed in the TER119+ erythroblasts. Hematopoietic cells from C4W and AKR mice did not absorb the F-SU/GFP as readily as the BALB/c cells, probably due to expression of the envelope glycoproteins of endogeneous Eco-MuLVs in these mice. Although AKR mice are susceptible to Eco-MuLV infection hile C4W mice are resistant, these mice showed no apparent difference in the F-SU/GFP-absorbing capacity. | |||||
| 書誌情報 |
Archives of Virology 巻 146, p. 507-519, 発行日 2001 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0304-8608 | |||||
