|
内容記述 |
Objective. In this study, we present the first dosimetric characterization of a novel OSL film in proton, carbon-ion, and electron beams, including signal-to-dose calibration and quantification of energy-dependent effects. Based on these results, the film can be applied for treatment quality assurance in particle therapy. Approach. Two BaFBr:Eu2+ OSL films were irradiated at HIMAC (Japan) using a passive scattering system for proton (p-HIMAC, 100, 160 MeV) and carbon ions (c-HIMAC, 290 MeV u−1); the PARTICLE center (Belgium) using a ProteusONE for protons (p-PARTICLE, 70, 100, 170 MeV); UZ Leuven (Belgium) using a TrueBeam linac for electrons (e-UZL, 6, 9, 12, 16 MeV). Measurements were taken at the beam plateau and Bragg Peak for ions and at dmax for electrons. A signal-to-dose calibration was performed within 1 to 8 Gy at the beam plateau for all nominal energies. LET-dependent effects were evaluated by quantifying the signal quenching at the Bragg peak relative to reference ionization chamber measurements. Proton and carbon depth-dose distributions were acquired for OSL and EBT3 films exposed through wedge phantoms. We obtained relative dose profiles that in case of p-PARTICLE exposures were compared to Monte Carlo calculations (RayStation). Main results. The signal-to-dose calibration was linear for each particle type, showing minimal variation across different nominal energies i.e., below 2% for p-PARTICLE (70–170 MeV), 4% for p-HIMAC, and 1% for e-UZL (9–16 MeV). The signal quenching at the Bragg preak was 2.2 (c-HIMAC), 1.4 (p-HIMAC), and 1.2 (p-PARTICLE). OSL and EBT3 films showed similar depth–dose profiles and quenching behavior. Significance. This OSL film can be calibrated with a single linear coefficient across clinically relevant particle beam energies. However, LET corrections, similar to those required for EBT3 films, are necessary for accurate dosimetry at the Bragg peak and for clinical use, such as quality assurance of intensity-modulated proton therapy. |
