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Knock-In Rat Model of the BRCA1 Pathogenic Variant p.L63X: Its Basic Phenotypes and Perspectives for Use in Cancer Prevention Research

https://repo.qst.go.jp/records/2003161
https://repo.qst.go.jp/records/2003161
cf0e6d74-71fd-41c1-a609-67074bed2bef
アイテムタイプ 会議発表論文 / Conference Paper(1)
公開日 2026-04-03
タイトル
タイトル Knock-In Rat Model of the BRCA1 Pathogenic Variant p.L63X: Its Basic Phenotypes and Perspectives for Use in Cancer Prevention Research
言語 en
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_5794
資源タイプ conference paper
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Imaoka Tatsuhiko

× Imaoka Tatsuhiko

Imaoka Tatsuhiko

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Nakamura Yuzuki

× Nakamura Yuzuki

Nakamura Yuzuki

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Nagata Kento

× Nagata Kento

Nagata Kento

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Yano-Nishimura Yukiko

× Yano-Nishimura Yukiko

Yano-Nishimura Yukiko

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Daino Kazuhiro

× Daino Kazuhiro

Daino Kazuhiro

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Ishikawa Atsuko

× Ishikawa Atsuko

Ishikawa Atsuko

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内容記述タイプ Abstract
内容記述 Animal models are key to obtaining insights into disease mechanisms and developing prophylactic and treatment measures. We have recently developed a rat model of BRCA1 deficiency and revealed that this model mimics many of the phenotypes in humans. Herein, we briefly review the development and characterization of the phenotypes of this model.
書誌情報 Practical Guide to Hereditary Breast and Ovarian Cancer IV - Annual Meeting of the Japanese Organization of Hereditary Breast and Ovarian Cancer 2024

p. 185-192, 発行日 2026-04
出版者
出版者 Springer Nature
DOI
識別子タイプ DOI
関連識別子 10.1007/978-981-95-6580-1_21
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