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Development of a Characteristic X-ray Imaging System for Dose-Relevant Assessment in At- 211 Targeted Alpha Therapy
https://repo.qst.go.jp/records/2003112
https://repo.qst.go.jp/records/20031125d6f9d0e-1093-419b-aadc-b9a5a43a41d9
| アイテムタイプ | 会議発表用資料 / Presentation(1) | |||||||||||||||||||
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| 公開日 | 2026-03-30 | |||||||||||||||||||
| タイトル | ||||||||||||||||||||
| タイトル | Development of a Characteristic X-ray Imaging System for Dose-Relevant Assessment in At- 211 Targeted Alpha Therapy | |||||||||||||||||||
| 言語 | en | |||||||||||||||||||
| 言語 | ||||||||||||||||||||
| 言語 | eng | |||||||||||||||||||
| 資源タイプ | ||||||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||||||||||||||||
| 資源タイプ | conference presentation | |||||||||||||||||||
| 著者 |
Lu Fan
× Lu Fan
× Hu Jun
× Kitamura Hisashi
× Kusumoto Tamon
× Yoshii Hiroshi
× Miroslaw Janik
× Kodaira Satoshi
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| 抄録 | ||||||||||||||||||||
| 内容記述 | Targeted alpha therapy (TAT) using astatine-211 (At-211) enables highly localized energy deposition owing to its high linear energy transfer and short particle range. However, these properties make evaluation of radionuclide distribution and dose-related information challenging, while conventional nuclear imaging is limited by the low photon emission yield of At-211.We explore a characteristic X-ray imaging approach for dose-relevant assessment in At-211 TAT. Instead of detecting alpha particles directly, the system focuses on secondary characteristic X-rays generated during decay processes, allowing for a compact imaging configuration. Monte Carlo simulations using PHITS were performed to examine the generation and spatial characteristics of these X-rays, and a prototype system is being developed with preliminary phantom studies in progress. | |||||||||||||||||||
| 会議概要(会議名, 開催地, 会期, 主催者等) | ||||||||||||||||||||
| 内容記述 | 第38回固体飛跡検出器研究会における成果発表 | |||||||||||||||||||
| 発表年月日 | ||||||||||||||||||||
| 日付 | 2026-03-26 | |||||||||||||||||||