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Development of next-generation positron emission tomography at QST

https://repo.qst.go.jp/records/2002935
https://repo.qst.go.jp/records/2002935
a4672c34-10fa-4a9c-8b94-a820ab8a9902
アイテムタイプ 会議発表用資料 / Presentation(1)
公開日 2026-03-03
タイトル
タイトル Development of next-generation positron emission tomography at QST
言語 en
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言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_c94f
資源タイプ conference presentation
著者 Tashima Hideaki

× Tashima Hideaki

Tashima Hideaki

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Yamaya Taiga

× Yamaya Taiga

Yamaya Taiga

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抄録
内容記述 Positron Emission Tomography (PET) is one of the most significant medical applications of positrons, enabling noninvasive imaging of physiological and biochemical processes in living organisms. It is widely used in clinical practice, clinical research, and a broad range of other research fields, including preclinical studies [1]. PET plays a crucial role in the early detection of cancer and neurodegenerative diseases such as Alzheimer’s disease, leveraging positron annihilation to generate high-resolution metabolic images.Despite its widespread adoption, PET technology continues to evolve, driven by ongoing research and development efforts worldwide to enhance its fundamental performance and expand its applications. In this presentation, we introduce next-generation PET systems and detector technologies being developed at QST to advance the medical utilization of positrons. Figure 1 highlights the representative developments: a recently commercialized helmet-type PET system for dedicated brain imaging (Figure 1a) [2] and the world’s first open PET system OpenPET which has recently entered clinical research for carbon-ion cancer therapy (Figure 1b) [3,4], whole gamma imaging (WGI) which integrates Compton imaging [5] and PET to enable imaging of various gamma rays (Figure 1c) [6,7], and Quantum PET which aims to visualize positron lifetime, particularly the positronium lifetime distribution within living organisms [8-10] (Figure 1d).These advancements enhance imaging capabilities for specific medical and research applications, further expanding the role of positrons in medical imaging.Figure 1 Representative developments at QST: (a) Helmet-type PET, commercialized for brain imaging, reprinted from [2] (CC BY 4.0); (b) human-scale OpenPET system, reprinted from [3] (CC BY 4.0); (c) WGI prototype, ©2020 Institute of Physics and Engineering in Medicine, reprinted with permission from [6]; (d) conceptual illustration of Quantum PET.References[1] S. R. Meikle et al., Phys. Med. Biol., 66, 06RM01 (2021).[2] G. Akamatsu et al., Phys. Med. Biol., 67, 225011 (2022).[3] H. Tashima et al., IEEE Trans. Rad. Plasm. Med. Sci., 5, 807-816 (2021).[4] T. Yamaya et al., Eur. Phys. J. Plus, 140, 203 (2025).[5] H. Tashima and T. Yamaya, IEEE Trans. Rad. Plasm. Med. Sci., 8, 853-866 (2024).[6] E. Yoshida et al., Phys. Med. Biol., 65, 125013 (2020).[7] T. Yamaya et al., PET Clin., 19, 83-93 (2024).[8] K. Shibuya et al., Commun. Phys., 3, 173 (2020).[9] S. Takyu et al., Applied Physics Express, 15, 106001 (2022).[10] S. Takyu et al., Nucl. Instr. Meth. Phys. Res. Sect. A, 1065, 169514 (2024).
会議概要(会議名, 開催地, 会期, 主催者等)
内容記述 The 20th International Conference on Positron Annihilation
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日付 2025-06-06
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