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A practical method for synthesizing [11C]methanesulfonyl chloride as radiolabeling agent
https://repo.qst.go.jp/records/2002837
https://repo.qst.go.jp/records/2002837a6eda773-ed61-4a71-a883-e94740e63620
| アイテムタイプ | 会議発表用資料 / Presentation(1) | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2026-02-19 | |||||||||||||||
| タイトル | ||||||||||||||||
| タイトル | A practical method for synthesizing [11C]methanesulfonyl chloride as radiolabeling agent | |||||||||||||||
| 言語 | en | |||||||||||||||
| 言語 | ||||||||||||||||
| 言語 | eng | |||||||||||||||
| 資源タイプ | ||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6670 | |||||||||||||||
| 資源タイプ | conference poster | |||||||||||||||
| 著者 |
Kumata Katsushi
× Kumata Katsushi
× Ogawa Masanao
× Nengaki Nobuki
× Xie Lin
× Zhang Ming-Rong
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| 抄録 | ||||||||||||||||
| 内容記述 | Methanesulfonyl chloride (CH3SO2Cl) is well known to be reactive with amines, alcohols and phenols. It has been reported that [11C]CH3SO2Clwas synthesized by 1) chaging [11C]CH3I into [11C]CH3Li and then treatment with sulfuryl chloride. 2) changing [11C]CH3I into [11C]CH3SH, followed by oxidization with Cl2 or MnO2 etc.1) However, the radiochemical yields of [11C]CH3SO2Cl by these methods remained unstable and some used agents are difficult to handle. Here, we reported a practical method for synthesizing [11C]CH3SO2Cl as a radiolabeling agent via [11C]CH3I. | |||||||||||||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||||||||||||
| 内容記述 | 欧州分子イメージング学会（EMIM2026） | |||||||||||||||
| 発表年月日 | ||||||||||||||||
| 日付 | 2026-03-24 | |||||||||||||||
