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Reinventing type 2 immunity in cancer
https://repo.qst.go.jp/records/2002785
https://repo.qst.go.jp/records/20027852c3bd28a-053d-4358-a616-cadf20725730
| アイテムタイプ | 学術雑誌論文 / Journal Article(1) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2026-02-18 | |||||||||||
| タイトル | ||||||||||||
| タイトル | Reinventing type 2 immunity in cancer | |||||||||||
| 言語 | en | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| 資源タイプ | journal article | |||||||||||
| 著者 |
Marek Wagner
× Marek Wagner
× Hiroyoshi Nishikawa
× Koyasu Shigeo
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| 抄録 | ||||||||||||
| 内容記述タイプ | Abstract | |||||||||||
| 内容記述 | It is increasingly recognized that our understanding of type 2 immunity has undergone a substantial transformation, uncovering its unprecedented functions. Beyond its traditional role in defense against parasitic helminth infections, type 2 immunity has now emerged to safeguard the host through additional mechanisms, including the suppression of excessive type 1 immune responses, regulation of tissue repair and maintenance of adipose tissue homeostasis. However, unlike type 1 immune responses, type 2 immunity is perceived as a potential promoter of tumorigenesis. Emerging evidence challenges this perspective, painting a more nuanced picture where type 2 immunity might protect against or even actively suppress tumor growth and progression. With this in mind, we explore discoveries that highlight the potential of type 2 immunity in reshaping the landscape of cancer immunotherapies. | |||||||||||
| 書誌情報 |
Nature 巻 637, 号 8045, p. 296-303, 発行日 2025-01 |
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| 出版者 | ||||||||||||
| 出版者 | Springer Nature | |||||||||||
| PubMed番号 | ||||||||||||
| 識別子タイプ | PMID | |||||||||||
| 関連識別子 | 39780006 | |||||||||||
| DOI | ||||||||||||
| 識別子タイプ | DOI | |||||||||||
| 関連識別子 | 10.1038/s41586-024-08914-2 | |||||||||||
