| アイテムタイプ |
会議発表用資料 / Presentation(1) |
| 公開日 |
2025-06-03 |
| タイトル |
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|
タイトル |
Research for Detecting Tyrosine Metabolism using DNP-NMR/MRI |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6670 |
|
資源タイプ |
conference poster |
| 著者 |
Kaneko Daichi
Saito Keita
池田 明夏里
大熊 宏昌
横山 順
Takakusagi Yoichi
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| 抄録 |
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内容記述 |
Real-time metabolic observation studies using various molecular probes are possible using the DNP (Dynamic Nuclear Polarization)-NMR (Nuclear Magnetic Resonance)/MRI (Magnetic Resonance Imaging) method. It is especially important to study various amino acids present in the body as molecular probes from the viewpoint of application to in vivo studies. Therefore, DNP-NMR/MRI research using labelled amino acids will expand the scope of future DNP-NMR/MRI applications. In this study, we have developed a technique to visualize the tyrosine oxidation pathway using a compound having 13C in the aromatic ring of tyrosine. This technique can be applied to the detection of tyrosine metabolism in vivo. |
| 会議概要（会議名, 開催地, 会期, 主催者等） |
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内容記述 |
Hyperpolarized Carbon-13 MRI Technology Development |
| 発表年月日 |
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日付 |
2025-04-03 |
