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Experimental assessment of novel PET detector components for online imaging of radioactive ion beams
https://repo.qst.go.jp/records/2001959
https://repo.qst.go.jp/records/20019593d3ff89f-d58a-487a-ba3e-c6cac0d2b039
| アイテムタイプ | 学術雑誌論文 / Journal Article(1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2025-12-22 | |||||||||
| タイトル | ||||||||||
| タイトル | Experimental assessment of novel PET detector components for online imaging of radioactive ion beams | |||||||||
| 言語 | en | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | journal article | |||||||||
| 著者 |
Hangyu Kang
× Hangyu Kang
× Yamaya Taiga
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| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | Objective. This work aims to evaluate the ability of novel detector components to measure with submillimeter resolution in beam positron emission tomography (PET) signals produced by 10C and 11C radioactive ion beams stopped in PMMA targets and to validate a simulation toolkit for reproducing beam physics and PET detector responses within the framework of the biomedical applications of radioactive ion beam (BARB) project. Approach. The PET system response was assessed by visualizing the radioactive distributions of the beams stopped in tissue surrogate phantoms, and the capacity of the simulation toolkit was evaluated by comparing the experimental results with simulations, both for the depth-dose distribution and PET imaging. Main results. The detector assembly accurately visualized the PET signal with submillimeter resolution, achieving theobjective of measuring the difference in the positron range between 10C and 11C. The simulation toolkit effectively reproduced the beam characteristics and detector responses, showing a high degree of agreement between the simulated and experimental PET profiles under different beam delivery conditions. Significance. These findings demonstrate the precision and reliability of thenovel in-beam PET detector technology and simulation toolkit for small animals, establishing a solid foundation for the second phase of the BARB project, which involves preclinical irradiation of living mice. | |||||||||
| 書誌情報 |
Physics in Medicine and Biology 巻 70, 号 19, 発行日 2025-12 |
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| ISSN | ||||||||||
| 収録物識別子タイプ | ISSN | |||||||||
| 収録物識別子 | 1361-6560 | |||||||||
| DOI | ||||||||||
| 識別子タイプ | DOI | |||||||||
| 関連識別子 | 10.1088/1361-6560/ae0674 | |||||||||
