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  1. 原著論文

Application of the Avrami-Dobrzyński model for mammary tumorigenesis in irradiated rats indicates new candidates for parametric cancer risk assessment

https://repo.qst.go.jp/records/2001774
https://repo.qst.go.jp/records/2001774
87ff73cb-0349-4afa-b17e-cb680757d231
アイテムタイプ 学術雑誌論文 / Journal Article(1)
公開日 2025-05-27
タイトル
タイトル Application of the Avrami-Dobrzyński model for mammary tumorigenesis in irradiated rats indicates new candidates for parametric cancer risk assessment
言語 en
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 Julianna KRASOWSKA

× Julianna KRASOWSKA

Julianna KRASOWSKA

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IMAOKA Tatsuhiko

× IMAOKA Tatsuhiko

IMAOKA Tatsuhiko

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Krzysztof W. FORNALSKI

× Krzysztof W. FORNALSKI

Krzysztof W. FORNALSKI

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抄録
内容記述タイプ Abstract
内容記述 The two-parametric Avrami-Dobrzyński model, originally based on the condensed matter physics for phase transitions, was applied to the cumulative populational mammary cancer data of laboratory rats. The joint effect of parity, irradiation and BRCA1 mutation on breast cancer incidence was analysed. The study showed that the proposed model fits well with the data points, however, the values of parameters differ regarding the investigated group of animals. It was concluded that both model’s parameters, which relate to the dimension of carcinogenesis dynamics and the age distribution, are good candidates for cancer risk assessment regarding different risk factors.
書誌情報 Radiation and Environmental Biophysics

巻 64, 号 2, p. 229-239, 発行日 2025-05
出版者
出版者 Springer Nature
ISSN
収録物識別子タイプ ISSN
収録物識別子 1432-2099
PubMed番号
識別子タイプ PMID
関連識別子 40192782
DOI
識別子タイプ DOI
関連識別子 10.1007/s00411-025-01125-3
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