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Antioxidant Activity of Planar Catechin Conjugated with Trolox
https://repo.qst.go.jp/records/2001295
https://repo.qst.go.jp/records/2001295d5248521-0cb9-4a8f-ae15-60d92a363256
| アイテムタイプ | 学術雑誌論文 / Journal Article(1) | |||||||||||||||||
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| 公開日 | 2024-11-29 | |||||||||||||||||
| タイトル | ||||||||||||||||||
| タイトル | Antioxidant Activity of Planar Catechin Conjugated with Trolox | |||||||||||||||||
| 言語 | en | |||||||||||||||||
| 言語 | ||||||||||||||||||
| 言語 | eng | |||||||||||||||||
| 資源タイプ | ||||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||
| 著者 |
Shimizu Wakana
× Shimizu Wakana
× Shoji Yoshimi
× Ohkubo Kei
× Ito Hiromu
× Nakanishi Ikuo
× Fukuhara Kiyoshi
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| 抄録 | ||||||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||||||
| 内容記述 | Planar catechin (PCat), a natural antioxidant with a fixed 3D catechin structure on a plane, exhibits radical-scavenging activity approximately five times stronger than the conventional catechin. We synthesized a compound, PCat-TrOH, by binding Trolox (TrOH), an α-tocopherol analog, to PCat to enhance its antioxidant effect against oxidative stress, such as lipid peroxidation. TrOH shows radical-scavenging activity about 6.5 times greater than PCat, and PCat-TrOH exhibited a similar level of radical-scavenging activity to TrOH. Additionally, PCat-TrOH demonstrated twice the radical-scavenging activity against reactive oxygen species compared to PCat or TrOH. This compound is also expected to exhibit an excellent antioxidant effect against lipid peroxidation caused by radical chain reactions, through interactions with vitamin C, similar to that in the case of α-tocopherol. | |||||||||||||||||
| 書誌情報 |
Antioxidants 巻 13, 号 10, p. 1165-1165, 発行日 2024-09 |
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| 出版者 | ||||||||||||||||||
| 出版者 | Multidisciplinary Digital Publishing Institute | |||||||||||||||||
| PubMed番号 | ||||||||||||||||||
| 識別子タイプ | PMID | |||||||||||||||||
| 関連識別子 | 39339462 | |||||||||||||||||
| DOI | ||||||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||||
| 関連識別子 | 10.3390/antiox13101165 | |||||||||||||||||