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  1. 原著論文

Antioxidant Activity of Planar Catechin Conjugated with Trolox

https://repo.qst.go.jp/records/2001295
https://repo.qst.go.jp/records/2001295
d5248521-0cb9-4a8f-ae15-60d92a363256
アイテムタイプ 学術雑誌論文 / Journal Article(1)
公開日 2024-11-29
タイトル
タイトル Antioxidant Activity of Planar Catechin Conjugated with Trolox
言語 en
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 Shimizu Wakana

× Shimizu Wakana

Shimizu Wakana

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Shoji Yoshimi

× Shoji Yoshimi

Shoji Yoshimi

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Ohkubo Kei

× Ohkubo Kei

Ohkubo Kei

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Ito Hiromu

× Ito Hiromu

Ito Hiromu

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Nakanishi Ikuo

× Nakanishi Ikuo

Nakanishi Ikuo

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Fukuhara Kiyoshi

× Fukuhara Kiyoshi

Fukuhara Kiyoshi

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抄録
内容記述タイプ Abstract
内容記述 Planar catechin (PCat), a natural antioxidant with a fixed 3D catechin structure on a plane, exhibits radical-scavenging activity approximately five times stronger than the conventional catechin. We synthesized a compound, PCat-TrOH, by binding Trolox (TrOH), an α-tocopherol analog, to PCat to enhance its antioxidant effect against oxidative stress, such as lipid peroxidation. TrOH shows radical-scavenging activity about 6.5 times greater than PCat, and PCat-TrOH exhibited a similar level of radical-scavenging activity to TrOH. Additionally, PCat-TrOH demonstrated twice the radical-scavenging activity against reactive oxygen species compared to PCat or TrOH. This compound is also expected to exhibit an excellent antioxidant effect against lipid peroxidation caused by radical chain reactions, through interactions with vitamin C, similar to that in the case of α-tocopherol.
書誌情報 Antioxidants

巻 13, 号 10, p. 1165-1165, 発行日 2024-09
出版者
出版者 Multidisciplinary Digital Publishing Institute
PubMed番号
識別子タイプ PMID
関連識別子 39339462
DOI
識別子タイプ DOI
関連識別子 10.3390/antiox13101165
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