| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2024-09-09 |
| タイトル |
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|
タイトル |
Development of gelatin nanoparticles for positron emission tomography diagnosis in pancreatic cancer |
|
言語 |
en |
| 言語 |
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|
言語 |
eng |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 著者 |
Sugo Yumi
Kimura Atsushi
Koizumi Tomoya
Oyama Kotaro
Taguchi Mitsumasa
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| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
In this study aqueous gelatin solutions were irradiated with γ-rays to produce nanoparticles with average diameters of 5?20 nm via a radiation crosslinking technique. The gelatin nanoparticles were labeled with 64Cu, exhibiting negative surface potentials. Furthermore, the nanoparticles were evaluated in vivo by injecting them into pancreatic tumor-bearing mice. Notably, the nanoparticles accumulated in the tumors. Hence, 64Cu-labeled gelatin nanoparticles show promise as a platform for next-generation PET imaging agents for pancreatic cancer. |
| 書誌情報 |
Radiochimica Acta
発行日 2024-09
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| 出版者 |
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出版者 |
De Gruyter |
| DOI |
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識別子タイプ |
DOI |
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関連識別子 |
10.1515/ract-2024-0304 |
