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Advances in Targeted Microbeam Irradiation Methods for Live Caenorhabditis elegans

https://repo.qst.go.jp/records/2001283
https://repo.qst.go.jp/records/2001283
877fcec1-6bb4-4469-8066-87c1c9c2dbc2
アイテムタイプ 学術雑誌論文 / Journal Article(1)
公開日 2024-10-25
タイトル
タイトル Advances in Targeted Microbeam Irradiation Methods for Live Caenorhabditis elegans
言語 en
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 Suzuki Michiyo

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Suzuki Michiyo

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抄録
内容記述タイプ Abstract
内容記述 Charged-particle microbeam irradiation devices, which can convert heavy-ion or proton beams into microbeams and irradiate individual animal cells and tissues, have been developed and used for bioirradiation in Japan, the United States, China, and France. Microbeam irradiation technology has been used to analyze the effects of irradiation on mammalian cancer cells, especially bystander effects. In 2006, individual-level microbeam irradiation of the nematode Caenorhabditis elegans was first realized using JAEA-Takasaki’s (now QST-TIAQS’s) TIARA collimated microbeam irradiation device. As of 2023, microbeam irradiation of C. elegans has been achieved at five sites worldwide (one in Japan, one in the United States, one in China, and two in France). This paper summarizes the global progress in the field of microbeam biology using C. elegans, while focusing on issues unique to microbeam irradiation of live C. elegans, such as the method of immobilizing C. elegans for mi-crobeam experiments.
書誌情報 Biology

巻 13, 号 11, p. 864, 発行日 2024-10
出版者
出版者 MDPI
ISSN
収録物識別子タイプ ISSN
収録物識別子 2079-7737
DOI
識別子タイプ DOI
関連識別子 10.3390/biology13110864
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