| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2024-02-13 |
| タイトル |
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タイトル |
Nano-quantum sensors-based imaging and sensing for target-based drug discovery and development |
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言語 |
ja |
| 言語 |
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言語 |
jpn |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 著者 |
Taisuke Shimada
植田 泰之
竹丸 ひかり
馬場 嘉信
湯川 博
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| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Biological imaging and sensing are vital for understanding the biochemical and biological processes related to drug discovery and development. Nano-quantum sensors such as quantum dots and fluorescent nanodiamonds are luminescent nanoparticle sensors with excellent optical properties originating from quantum effects, and these sensors are promising for long-term imaging and physicochemical sensing with high spatiotemporal resolution. However, owing to the requirements of biological compatibility and target specificity for such sensor applications, modifying the sensor surfaces is essential. Moreover, owing to the demand for imaging- and sensing-assisted therapies (theranostics), a combination of nano-quantum sensors and therapeutic agents has been developed via surface modifications. We herein outline advanced surface modifications of nano-quantum sensors and their applications in in vitro and in vivo imaging, sensing, and therapy for target-based drug discovery and development. |
| 書誌情報 |
TrAC Trends in Analytical Chemistry
巻 171,
発行日 2024-02
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| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
1879-3142 |
| DOI |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1016/j.trac.2023.117496 |
