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Carbon Ion Radiotherapy: An Evidence-Based Review and Summary Recommendations of Clinical Outcomes for Skull-Base Chordomas and Chondrosarcomas.
https://repo.qst.go.jp/records/2001016
https://repo.qst.go.jp/records/2001016825d34e4-0df6-4192-a092-c95d3b9fcf56
| アイテムタイプ | 学術雑誌論文 / Journal Article(1) | |||||||||||||||||||||||||||||||||||
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| 公開日 | 2024-02-05 | |||||||||||||||||||||||||||||||||||
| タイトル | ||||||||||||||||||||||||||||||||||||
| タイトル | Carbon Ion Radiotherapy: An Evidence-Based Review and Summary Recommendations of Clinical Outcomes for Skull-Base Chordomas and Chondrosarcomas. | |||||||||||||||||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||||||||||||||||
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| 言語 | eng | |||||||||||||||||||||||||||||||||||
| 資源タイプ | ||||||||||||||||||||||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||||||||||||||||||||
| 著者 |
Adam L Holtzman
× Adam L Holtzman
× Katharina Seidensaal
× Alberto Iannalfi
× Kyung Hwan Kim
× Masashi Koto
× Wan-Chin Yang
× Cheng-Ying Shiau
× Anita Mahajan
× Safia K Ahmed
× Daniel M Trifiletti
× Jennifer L Peterson
× Daniel M Koffler
× Laura A Vallow
× Bradford S Hoppe
× Michael S Rutenberg
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| 抄録 | ||||||||||||||||||||||||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||||||||||||||||||||||||
| 内容記述 | Skull-base chordoma and chondrosarcoma are rare radioresistant tumors treated with surgical resection and/or radiotherapy. Because of the established dosimetric and biological benefits of heavy particle therapy, we performed a systematic and evidence-based review of the clinical outcomes of patients with skull-base chordoma and chondrosarcoma treated with carbon ion radiotherapy (CIRT). A literature review was performed using a MEDLINE search of all articles to date. We identified 227 studies as appropriate for review, and 24 were ultimately included. The published data illustrate that CIRT provides benchmark disease control outcomes for skull-base chordoma and chondrosarcoma, respectively, with acceptable toxicity. CIRT is an advanced treatment technique that may provide not only dosimetric benefits over conventional photon therapy but also biologic intensification to overcome mechanisms of radioresistance. Ongoing research is needed to define the magnitude of benefit, patient selection, and cost-effectiveness of CIRT compared to other forms of radiotherapy. | |||||||||||||||||||||||||||||||||||
| 書誌情報 |
Cancers 巻 15, 号 20, 発行日 2023-10 |
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| 出版者 | MDPI | |||||||||||||||||||||||||||||||||||
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| 収録物識別子タイプ | ISSN | |||||||||||||||||||||||||||||||||||
| 収録物識別子 | 2072-6694 | |||||||||||||||||||||||||||||||||||
| PubMed番号 | ||||||||||||||||||||||||||||||||||||
| 識別子タイプ | PMID | |||||||||||||||||||||||||||||||||||
| 関連識別子 | 37894388 | |||||||||||||||||||||||||||||||||||
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| 識別子タイプ | DOI | |||||||||||||||||||||||||||||||||||
| 関連識別子 | 10.3390/cancers15205021 | |||||||||||||||||||||||||||||||||||
